The Journal of Alternative and Complementary Medicine
October 1, 2017
Ava LaVonne Vinesett, Riitta Rutanen Whaley, Cheryl L. Woods-Giscombé et al.
Indigenous people's ceremonies using rhythm and dance have been used for countless generations throughout the world for healing, conflict resolution, social bonding, and spiritual experience. A previous study reported that a ceremony based on the Central African ngoma tradition was favorably received by a group of Americans. The present trial compared the effects of the modified ngoma ceremony...
Journal of Psychopharmacology
October 1, 2017
Cameron Castle, Andrew Gray, Shona Neehoff et al.
20 citations
Patients receiving ketamine for refractory depression and anxiety report dissociative symptoms in the first 60 min post-dose. The most commonly used instrument to assess this is the Clinician-Administered Dissociative States Scale (CADSS), developed based on the assessment of patients with dissociative symptoms. Its psychometric properties for ketamine-induced dissociation have not been...
TIPS - Trends in Pharmacological Sciences
September 22, 2017
Evan J. Kyzar, Charles D. Nichols, Raul R. Gainetdinov et al.
155 citations
Psychedelic drugs, such as lysergic acid diethylamide (LSD), mescaline, and psilocybin, exert profound effects on brain and behavior. After decades of difficulties in studying these compounds, psychedelics are again being tested as potential treatments for intractable biomedical disorders. Preclinical research of psychedelics complements human neuroimaging studies and pilot clinical trials,...
Psychiatric Clinics of North America
September 18, 2017
Stefan G Hofmann, Angelina F Gómez
Synopsis This article reviews the ways in which cognitive and behavioral treatments for depression and anxiety have been advanced by the application of mindfulness practices. Research on mindfulness-based interventions (MBIs) has increased exponentially in the past decade. The most common include Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT). MBIs have...
Psychopharmacology
September 16, 2017
Yasmin Schmid, Matthias E. Liechti
234 citations
RATIONALE: Lysergic acid diethylamide (LSD) and other serotonergic hallucinogens can induce profound alterations of consciousness and mystical-type experiences, with reportedly long-lasting effects on subjective well-being and personality. METHODS: We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The...
Religions
September 14, 2017
John Bartkowski, Gabriel Acevedo, Harriet Van Loggerenberg
Durkheim argued that religion’s emphasis on the supernatural combined with its unique ability to foster strong collective bonds lent it power to confer distinctive social benefits. Subsequent research has confirmed these propositions with respect to religion and mental health. At the same time, meditation has been linked to mental health benefits in intervention-based studies. Our investigation...
September 2, 2017
J. Dickinson, Philippa M. Friary, C. McCann
ABSTRACT Background: Anxiety goes largely undetected and undiagnosed in the aphasia population. Mindfulness programmes have been shown to be effective in reducing anxiety in populations with chronic disorders. These interventions have also shown effects on cognitive functioning including attention, executive function and working memory. Aims: To identify the impact of reduced anxiety using...
Noro psikiyatri arsivi
September 1, 2017
Çağdaş Yokuşoğlu, Mücahit Atasoy, Nurgül Tekeli et al.
The aim of this study was to examine the level of lucidity and its relation with metacognitive beliefs and dream anxiety in medical students. Nine hundred sixteen medical students were enrolled in the study. The participants were assessed with the Lucidity and Consciousness in Dreams Scale (LuCiD), the Metacognition Questionnaire-30 (MCQ-30), and the Van Dream Anxiety Scale (VDAS). There was no...
Journal of Evidence-Based Complementary & Alternative Medicine
August 30, 2017
Catherine Malboeuf-Hurtubise, Éric Lacourse, Catherine Herba et al.
Mindfulness-based interventions constitute a promising option to address anxiety and depression in elementary school students. This study evaluated the effect of a mindfulness-based intervention on anxiety and depression in elementary school students with a diagnosis of anxiety or depression disorder. A single-subject experimental A-B-A design was used. Participants were three elementary school...
Neuropsychopharmacology
August 29, 2017
Jerome H Taylor, Angeli Landeros‐Weisenberger, Catherine Coughlin et al.
Many patients with social anxiety disorder (SAD) experience inadequate symptom relief from available treatments. Ketamine is a potent N-methyl-D-aspartate receptor antagonist with a potentially novel mechanism of action for the treatment of anxiety disorders. Therefore, we conducted a double-blind, randomized, placebo-controlled crossover trial in 18 adults with DSM-5 SAD and compared the...
Frontiers in Psychiatry
August 25, 2017
J. Douglas Bremner, Sanskriti Mishra, Carolina Campanella et al.
81 citations
OBJECTIVE: Brain imaging studies in patients with post-traumatic stress disorder (PTSD) have implicated a circuitry of brain regions including the medial prefrontal cortex, amygdala, hippocampus, parietal cortex, and insula. Pharmacological treatment studies have shown a reversal of medial prefrontal deficits in response to traumatic reminders. Mindfulness-based stress reduction (MBSR) is a...
Psychological Medicine
August 25, 2017
Philip J. Cowen
38 citations
Pragmatic studies indicate that a substantial number of depressed patients do not remit with current first-line antidepressant treatments and after two failed treatment steps the chance of remission with subsequent therapies is around 15%. This paper focuses on current evidence for pharmacological treatments in resistant depression as well as possible future developments. For patients who have...
Neuroscience
August 24, 2017
Zhiyi Chen, Yiqun Guo, Tingyong Feng
Resting-state functional Magnetic Resonance Imaging (rs-fMRI) is frequently used as a powerful technology to detect individual differences in many cognitive functions. Recently, some studies have explored the association between scale-free dynamic properties of resting-state brain activation and individual personality traits. However, little is known about whether the scale-free dynamics of...
Journal of Psychiatric Research
August 23, 2017
Michaela C. Pascoe, David R Thompson, Zoe M Jenkins et al.
Meditation is a popular form of stress management, argued to mediate stress reactivity. However, many studies in this field commonly fail to include an active control group. Given the frequency with which people are selecting meditation as a form of self-management, it is important to validate if the practice is effective in mediating stress-reactivity using well-controlled studies. Thus, we...
JAMA
August 14, 2017
Samuel T. Wilkinson, Gerard Sanacora
36 citations
This Viewpoint summarizes a number of important issues related to the clinical use of ketamine for the treatment of psychiatric disorders addressed in the consensus statement and provides suggestions for addressing remaining concerns.
Drug and Alcohol Dependence
August 1, 2017
Emma Childs, Joseph A Lutz, Harriet de Wit
Cannabis smokers often report that they use the drug to relax or to relieve emotional stress. However, few clinical studies have shown evidence of the stress-relieving effects of cannabis or cannabinoid agonists. In this study, we sought to assess the influence of delta-9-tetrahydrocannabinol (THC), a main active ingredient of cannabis, upon emotional responses to an acute psychosocial stressor...
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
July 28, 2017
Robson Savoldi, Daniel Polari, Jaquelinne Pinheiro‐da‐silva et al.
The combined infusion of Banisteriopsis caapi stem and Psychotria viridis leaves, known as ayahuasca, has been used for centuries by indigenous tribes. The infusion is rich in N, N-dimethyltryptamine (DMT) and monoamine oxidase inhibitors, with properties similar to those of serotonin. Despite substantial progress in the development of new drugs to treat anxiety and depression, current...
Frontiers in Behavioral Neuroscience
July 28, 2017
Robson Savoldi, Daniel Polari, Jaquelinne Pinheiro‐da‐silva et al.
38 citations
The combined infusion of Banisteriopsis caapi stem and Psychotria viridis leaves, known as ayahuasca, has been used for centuries by indigenous tribes. The infusion is rich in N, N-dimethyltryptamine (DMT) and monoamine oxidase inhibitors, with properties similar to those of serotonin. Despite substantial progress in the development of new drugs to treat anxiety and depression, current...
Social Psychiatry and Psychiatric Epidemiology
July 15, 2017
Stephanie Rek, Bryony Sheaves, Daniel K. Freeman
54 citations
Nightmares are inherently distressing, prevent restorative sleep, and are associated with a number of psychiatric problems, but have rarely been the subject of empirical study. Negative affect, linked to stressful events, is generally considered the key trigger of nightmares; hence nightmares have most often been considered in the context of post-traumatic stress disorder (PTSD). However, many...
Behavioural Brain Research
July 14, 2017
Allan V. Kalueff, Aleksandra Kaluyeva, Émeline L. Maillet
21 citations
Noribogaine is the main psychoactive metabolite of the hallucinogenic drug ibogaine, and is a particularly interesting compound potentially useful to treat dependence and various psychiatric disorders. Here, we report the effects of noribogaine on anxiety and locomotion in zebrafish (Danio rerio), a new promising model organism in neurobehavioral and psychopharmacological research. Adult...