Nidrâ yoga is an ancient yogic practice capable of inducing altered states of consciousness characterized by deep relaxation, strong concentration, acute self-awareness, and joy. In modern contemplative neuroscience language, it is known by the name yoga nidra, and few studies have investigated its phenomenological and psychophysiological effects. Six healthy volunteers (four females aged...
Psychedelics are drugs that alter consciousness and affect human psyche. 5-Methoxy- N,N -diisopropyltryptamine (5-MeO-DIPT) emerged in the recreational drug market with the street name “foxy” and has been increasingly used as a substitute for methylenedioxymethamphetamine (MDMA) Methylenedioxymethamphetamine (MDMA) . 5-MeO-DIPT is a competitive inhibitor of the serotonin (5-HT) transporter...
Case report notions of unexpected memory retrieval in patients with severe dementia near to death are starting to alter the central "irreversible" paradigm of dementia and locate dementia as a problem of memory retrieval, not consolidation. We suggest that the most likely central tenet of this paradoxical memory retrieval is the fluctuation of neuromodulators projecting from the brain stem to...
5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) is a tryptamine with ultra-rapid onset and short duration of psychedelic effects. Prospective studies for other tryptamines have suggested beneficial effects on mental health outcomes. In preparation for a study in patients with depression, the present study GH001-HV-101 aimed to assess the impact of four different dose levels of a novel vaporized...
At present, the science of consciousness is structured around the search for the neural correlates of consciousness (the NCCs). One of the alleged advantages of the NCCs framework is its metaphysical neutrality—the fact that it begs no contested questions with respect to debates about the fundamental nature of consciousness. Here, we argue that even if the NCC framework is metaphysically...
Summary: Functional dissociations in the brain observed during non-rapid eye movement (NREM) sleep have been associated with reduced information integration and impaired consciousness that accompany increasing sleep depth. Here, we explored the dynamical properties of large-scale functional brain networks derived from transient brain activity using functional magnetic resonance imaging. Spatial...
Peripersonal space (PPS) is defined as the space surrounding the body where we can reach or be reached by external entities, including objects or other individuals. PPS is an essential component of bodily self-consciousness that allows us to perform actions in the world (e.g., grasping and manipulating objects) and protect our body while interacting with the surrounding environment....
Kambô, the secretion of the Amazonian Giant Leaf Frog (Phyllomedusa bicolor) contains a plethora of bioactive peptides and was originally used by indigenous communities from the Amazon basin as medicine for improving hunting capacities. In the last 20 years, Kambô has spread to Western urban healing circles. To date it is still controversial whether the acute effects of Kambô include...
This is a review of the book Mozg - kultura - socium. Kantianskaya programma v cognitivnykh issledovaniyakh by Bazhanov V.A. The author`s main aim is a reconsideration of some fundamental principles of epistemology and philosophy of science in the light of state-of-the-art advancements of neurosciences. According to the author of the book, social and cultural revolution in neurosciences has...
Abstract The dynamical approach represents a new branch in the understanding of functional brain networks. Using simple indices to represent time connectivity and topological stability, we evaluated the hypothesis of increased brain stability during the meditative state in comparison to the relaxation state. We used a new way to consider the time evolution of synchronization patterns in...