Introduction Numerous studies have shown a link between hypnotic susceptibility, the hypnotically altered state of consciousness, and the intensity of experienced emotions (De Pascalis et al., 1987; De Pascalis, Marucci, & Penna, 1989; Bryant & McConkey, 1989; Crowson, Conroy, & Chester, 1991; Crawford, Kapelis, & Harrison, 1995). One of the most suitable experimental psychological methods for...
ZUSAMMENFASSUNG Psychedelika stoßen in der Psychiatrie auf ein erneut zunehmendes fachliches und wissenschaftliches Interesse. Nach einer intensiveren Phase des Einsatzes im psychotherapeutischen Kontext Mitte des letzten Jahrhunderts kam die Forschung in dem Bereich nach gesetzlichen Verboten weitestgehend zum Erliegen. Erst seit wenigen Jahren wird das klinische Potenzial wieder mit modernen...
Recent studies and anecdotal reports suggest that psychedelics can improve mood states, even at low doses. However, few placebo-controlled studies have examined the acute effects of low doses of LSD in individuals with psychiatric symptoms. In the current study, we examined the acute and sub-acute effect of a low dose of LSD (26 µg) on subjective effects and mood in volunteers with mild...
PsychoactivesMarch 31, 2024Rishma S. I. Khubsing, Martin van Leerdam, Eline Haijen et al.3 citations
Background: In recent years, there has been a growing interest in the therapeutic potential of classical psychedelics like ayahuasca for mental health improvement. Naturalistic studies at ayahuasca retreats have shown (short-term) improvements in mental well-being but understanding the psychological mechanisms is crucial. We are interested in psychological processes such as resilience,...
Consciousness has intrigued philosophers and scholars for millennia and has been the topic of considerable scientific investigation in recent decades. Despite its importance, there is no unifying definition of the term, nor are there widely accepted measures of consciousness. Indeed, it is likely that consciousness-by its very nature-eludes measurement. It is, however, possible to measure how...
Abstract As reliable facilitators of characteristically unique altered states of consciousness that are notoriously difficult to comprehend, psychedelics naturally attract a multidisciplinary scope for their research, with direct relevance to neuroscience, pharmacology, psychology, as well as philosophy of mind, metaphysics, and epistemology — disciplines united by the common inquiry into the...
In a double-blinded cross-over design, 30 adults (mean age = 25.57, SD = 3.74; all male) were administered racemic ketamine and compared against saline infusion as a control. Both task-driven (auditory oddball paradigm) and resting-state EEG were recorded. HOI were computed using advanced multivariate information theory tools, allowing us to quantify nonlinear statistical dependencies between...
Abstract Introduction Psychedelics have garnered increased attention as potential therapeutic options for various mental illnesses. Previous studies reported that psychedelics cause psychoactive effects through mystical experiences induced by these substances, including an altered state of consciousness. While this phenomenon is commonly assessed by the Mystical Experiences Questionnaire...
Introduction: Effective blinding is especially challenging in randomized controlled trials (RCTs) involving psychedelics due to the inherent alterations in consciousness that these compounds induce. In this systematic review and exploratory analysis, we aim at synthesizing the methodologies used in RCTs involving classic psychedelics and identify procedures that can help minimize unblinding and...
Psychedelics can profoundly alter cognition and consciousness. Their use in Middle Eastern countries, including Iraq, is ambiguous. We aim to investigate psychedelic awareness and use among Iraqi and Polish medical students. We surveyed 739 university students from Poland (315) and Iraq (424) using 31 adapted questions from the European School Survey Project on Alcohol and Other Drugs (ESPAD)....