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Addiction: all studies

Page 728 of 857: studies 7,271 to 7,280 of 8,563, newest first. Back to the addiction overview

Research

Electrophysiological characterization of harmane-induced activation of mesolimbic dopamine neurons.

European Journal of Pharmacology March 10, 2010 Ouafa Arib, Pascal Rat, Robert Molimard et al.

It has been suggested that the beta-carbolines harmane and norharmane may be involved in the pathophysiology of Parkinson's disease, psychosis and addiction, but the mechanisms of these possible effects remain to be elucidated. In the present study, the effects of the two compounds were examined by using in vivo extracellular recordings of ventral tegmental dopamine neurons. The effects of...

BOLD Signal in Both Ipsilateral and Contralateral Retinotopic Cortex Modulates with Perceptual Fading

PLoS One March 10, 2010 Po‐jang Hsieh, Peter Ulric Tse 4 citations

UNLABELLED: Under conditions of visual fixation, perceptual fading occurs when a stationary object, though present in the world and continually casting light upon the retina, vanishes from visual consciousness. The neural correlates of the consciousness of such an object will presumably modulate in activity with the onset and cessation of perceptual fading. METHOD: In order to localize the...

The role of monoamines in the changes in body temperature induced by 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) and its derivatives

British Journal of Pharmacology March 3, 2010 James R. Docherty, Ar Green 88 citations

Hyperthermia is probably the most widely known acute adverse event that can follow ingestion of 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) by recreational users. The effect of MDMA on body temperature is complex because the drug has actions on all three major monoamine neurotransmitters [5‐hydroxytryptamine (5‐HT), dopamine and noradrenaline], both by amine release and by direct receptor...

Exploring the Dao-field

Transformative Dialogues Teaching and Learning Journal March 1, 2010 Sean S. Park, Avraham Cohen

Drawing from practices of mindfulness, martial arts, and psychotherapy, we present a dialogue and inquiry into how educators can attend to experience through inner work.It is our conviction that schools that undertake education as a participatory endeavour in both knowledge and knowing, having and being, will depend greatly on our capacity, as educators, to see and attend to the different, yet...

Nightmares and bad dreams in patients with borderline personality disorder: Fantasy as a coping skill?

The European Journal of Psychiatry March 1, 2010 Péter Simor, Szilvia Csóka, Róbert Bódizs 35 citations

Background and Objectives: Previous studies reported a high prevalence of nightmares and dream anxiety in Borderline Personality Disorder (BPD) and the severity of dream disturbances correlated with daytime symptoms of psychopathology. However, the majority of these results are based on retrospective questionnaire-based study designs, and hence the effect of recall biases (characteristic for...

State Effects of Two Forms of Meditation on Prefrontal EEG Asymmetry in Previously Depressed Individuals

Mindfulness March 1, 2010 Thorsten Barnhofer, Tobias Chittka, Helen Nightingale et al. 99 citations

We investigated state effects of two forms of meditation on electroencephalography prefrontal α-asymmetry, a global indicator of approach versus withdrawal motivation and related affective state. A clinical series of previously depressed individuals were guided to practice either mindfulness breathing meditation (N = 8) or a form of meditation directly aimed at cultivating positive affect,...

The history of ergot of rye (Claviceps purpurea) III: 1940-80.

The journal of the Royal College of Physicians of Edinburgh March 1, 2010 M R Lee 20 citations

The period 1940-80 in the history of ergot was dominated by two investigators, Arthur Stoll and Albert Hofmann. There was great excitement when their group isolated from ergot preparations the powerful psychotropic agent lysergic acid diethylamide (LSD). It was thought that this substance would help to find the cause of schizophrenia and other psychotic disorders, but it would prove to be a...

DOI: 10.4997/jrcpe.2010.115 (opens in new tab) Full text (opens in new tab) Ergot alkaloids Medical therapies Pharmacology

The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen

Psychopharmacology February 19, 2010 Clinton E. Canal, U. B. Olaghere da Silva, Paul J Gresch et al. 111 citations

RationaleHallucinogenic serotonin 2A (5-HT2A) receptor partial agonists, such as (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI), induce a frontal cortex-dependent head-twitch response (HTR) in rodents, a behavioral proxy of a hallucinogenic response that is blocked by 5-HT2A receptor antagonists. In addition to 5-HT2A receptors, DOI and most other serotonin-like...

The Impact of Dream Interpretation Using Psychological Kinesiology on the Frequency of Recurring Dreams

Psychotherapy and Psychosomatics February 18, 2010 Douglas E. Webb, Joen Fagan 10 citations

Subjects reporting a recurring dream at least 4 times a month for a year or more were assigned to a dream recording control group and an experimental group which used muscle testing to guide dream interpretation. Dream frequency was recorded prior to and following a dream interpretation intervention (experimental subjects) or dream reporting session (control subjects). Dream frequency declined...

Induction of energy metabolism related enzymes in yeast Saccharomyces cerevisiae exposed to ibogaine is adaptation to acute decrease in ATP energy pool.

European Journal of Pharmacology February 10, 2010 Roman Paškulin, Polona Jamnik, Natasa Obermajer et al. 13 citations

Ibogaine has been extensively studied in the last decades in relation to its anti-addictive properties that have been repeatedly reported as being addiction interruptive and craving eliminative. In our previous study we have already demonstrated induction of energy related enzymes in rat brains treated with ibogaine at a dose of 20mg/kg i.p. 24 and 72 h prior to proteomic analysis. In this...