May 27, 2020
A. Bullock, A. Burns, Anna Alkozei et al.
Disturbing dreams and nightmares are common in individuals with post-traumatic stress disorder (PTSD). At present, little research has investigated the associations between nightmares and cognition in these individuals. However, a robust body of research has shown memory and attention impairments among those with PTSD. The present study sought to investigate the potential relationships between...
Sleep
May 27, 2020
M Gross, R Patel, S W Schwartz et al.
Abstract Introduction In the James A. Haley Veterans Administration (JAHVA) Vista database, the ICD-9 code 307.47 for Nightmare disorder (ND) is infrequently used and appears independently of codes for PTSD. We wanted to determine if certain drugs that may affect sleep are associated with ND. Methods All patients with ND visiting JAHVA between 2007 and 2011 were selected along with control...
Ethnic and Racial Studies
May 27, 2020
Ori Mautner, Nissim Mizrachi
ABSTRACT Insight meditation (vipassanā) originated in Theravāda Buddhism. However, participants in a “Jewish Vipassanā” meditation retreat – held at a Jewish settlement in the West Bank region controlled by Israel since 1967 – often depicted vipassanā as essentially Jewish. Indeed, to validate their adoption of insight meditation, many participants first needed to establish their exclusive...
Journal of Medical Ethics
May 27, 2020
William Smith, Dominic Sisti
142 citations
Despite the fact that psychedelics were proscribed from medical research half a century ago, recent, early-phase trials on psychedelics have suggested that they bring novel benefits to patients in the treatment of several mental and substance use disorders. When beneficial, the psychedelic experience is characterized by features unlike those of other psychiatric and medical treatments. These...
Addiction Biology
May 26, 2020
David Martin, Utsav Gyawali, Donna J. Calu
The relative value of and motivation for abused drugs often increases with drug experience and differs based on drug availability. Here, we determined how different intake patterns of fentanyl, a μ‐opioid agonist, alter economic demand for fentanyl and how 5‐HT2A receptor stimulation affects economic demand for fentanyl. We used a within‐session demand threshold procedure to characterize...
Global Advances in Health and Medicine
May 21, 2020
Paul J Mills, Tiffany J Barsotti, Judith Blackstone et al.
18 citations
Integrative Health aims to treat the whole person and to do so within the context of whole systems and practices. We raise questions as to what constitutes the whole person and what must be taken into account to support the creation of optimal well-being. We propose that in order to fully account for the whole person, the transcendent aspects of human awareness, the development of which is the...
May 20, 2020
Helen Bequaert Holmes
The perinatal period of birth is examined through a psychoanalytic lens, namely through Freud’s depiction of the ‘oceanic feelings’, the source of religious energy in this view and a possible perceived connection with a deity by the foetus. Khamsi supports the possibility of such a foetal experience but also proposes its contrary, namely that the traditional opinion denies that neonates are...
Schizophrenia Bulletin
May 18, 2020
Gabrielle Pochiet, Katie Lavigne, Ashok Malla et al.
Abstract Background Although growing research has observed a positive association between cannabis consumption and cognition in patients with first-episode psychosis (FEP), such better performance has not always been found across all cognitive domains. Furthermore, it remains unclear whether frequency of use is related to cognitive functioning in a dose-dependent manner. Understanding these...
Journal of the Neurological Sciences
May 15, 2020
Molly C Kalmoe, Alvin Janski, Charles F Zorumski et al.
N-methyl-d-aspartate receptor (NMDAR) antagonists, including ketamine and nitrous oxide, are currently intensely studied as rapid-acting antidepressant agents. Interestingly, both of these compounds are also drugs of abuse. Intravenous ketamine, a dissociative anesthetic that induces complex downstream effects via NMDARs, rapidly reduces depressive and suicidal symptoms in treatment-resistant...
Drug and Alcohol Dependence
May 15, 2020
R. Yockey, Rebecca A. Vidourek, Keith A. King
111 citations
BACKGROUND The recent use of LSD to treat severe psychological disorders in several clinical applications has proven effective in reducing symptoms and distressing events. Trend analyses are warranted to provide the most current data for clinical and health interventions. The purpose of this study was to examine trends in LSD use among adults in the United States. METHODS A secondary analysis...