Frontiers in Forests and Global Change
May 23, 2022
Dominique Strauss, Soumya Ghosh, Zurika Murray et al.
30 citations
Psilocybin and psilocin, two psychoactive components found in “magic mushrooms,” have therapeutic potential in a number of mental health disorders without the addictiveness and overdose risks found in other mind-altering drugs, such as cocaine, methamphetamines and alcohol. Psychedelic mushrooms occur naturally, are wide distributed and easily accessible. The need for reviews and comprehensive...
Frontiers in Psychology
May 23, 2022
David B. Yaden, Dylan Earp, Marianna Graziosi et al.
106 citations
The acute subjective effects of psychedelics are responsive to users’ expectations and surroundings (i.e., “set and setting”). Accordingly, a great deal of thought has gone into designing the psychosocial context of psychedelic administration in clinical settings. But what theoretical paradigms inform these considerations about set and setting? Here, we describe several historical, sociological...
Neuroscience & Biobehavioral Reviews
May 21, 2022
Vince Polito, Paul Liknaitzky
110 citations
The use of low doses of psychedelic substances (microdosing) is attracting increasing interest. This systematic review summarises all empirical microdosing research to date, including a set of infrequently cited studies that took place prior to prohibition. Specifically, we reviewed 44 studies published between 1955 and 2021, and summarised reported effects across six categories: mood and...
Journal of Psychopharmacology
May 20, 2022
Matthew B. Wall, Tom P. Freeman, Chandni Hindocha et al.
21 citations
Background: Cannabidiol (CBD) and Δ 9 -tetrahydrocannabinol (THC) are the two major constituents of cannabis with contrasting mechanisms of action. THC is the major psychoactive, addiction-promoting, and psychotomimetic compound, while CBD may have opposite effects. The brain effects of these drugs alone and in combination are poorly understood. In particular, the striatum is implicated in the...
Digital Archive @ GSU
May 17, 2022
Emilie Seena
BACKGROUND: The use of complementary and alternative medicine (CAM) has dramatically increased over the years since 1990. It is one of the fastest growing fields in healthcare and it is widely used today in the United States. Most people utilizing CAM approaches are seeking ways to improve overall health and well-being to relieve symptoms associated with body aches such as neck and back pain,...
Translational Psychiatry
May 17, 2022
Satoshi Deyama, M. Kondo, Shoichi Shimada et al.
Ketamine, an N-methyl-D-aspartate receptor antagonist, exerts rapid and sustained antidepressant actions. Preclinical studies demonstrated that the release of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor in the medial prefrontal cortex (mPFC) is essential for the antidepressant-like effects of ketamine. However, the role of other neurotrophic factors in the...
The Journal of Neuropsychiatry and Clinical Neurosciences
May 17, 2022
Matthew Butler, Mathieu Seynaeve, Abigail Bradley‐Westguard et al.
6 citations
Objective: Functional neurological disorder (FND) causes a high burden of disability and distress. Although it is a common disorder, there is a pressing need for improved access to evidence-based treatments. With difficulties in finding effective treatment, some people with FND may seek alternative means of symptom relief, such as legal and illicit psychoactive substances, although the...
Frontiers in Public Health
May 13, 2022
Anna Dysart, Samantha M. Harden
7 citations
Background: Mindfulness and self-care, practiced through a variety of methods like meditation and exercise, can improve overall sense of holistic well-being (i.e., flourishing). Increasing mindfulness and self-care may lead to increased flourishing and job satisfaction among the nation-wide Cooperative Extension system delivery personnel (agents) through a theory-based online program and an...
Religions
May 13, 2022
An-ning Chen, Nicole Porter, Yue-Zhong Tang
This paper examines the spaces where Buddhist spiritual activity—specifically mindfulness practice—takes place, exploring how contemporary urban Buddhist contemplative places may benefit people’s mindful experience. Historical Buddhist contemplative places are examined through a literature review of Buddhist philosophy and Buddhist architecture and landscape. A case study of Kagyu Samye Dzong...
Acta bio-medica
May 11, 2022
Diego Dal Sacco
The ability to remember dreams can depend on a wide range of factors such as personality, creativity, mental state, cognitive functions as well as somatic symptoms. In the course of their studies, medical researchers have demonstrated that about 80% patients, woken up at their Rapid Eye Movement (REM) sleep phase, can remember their own dreams, whereas, in clinical practice, young adults can...