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Marianna Graziosi

9 papers in the library · 289 citations · publishing 2020-2025

Papers

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Informed Consent Documents from Psychedelic Clinical Trials: A Descriptive Ethical Analysis.

AJOB empirical bioethics July 16, 2025 Katherine Cheung, Caleigh Propes, Marianna Graziosi et al. 4 citations

Classic psychedelics, such as psilocybin and LSD, evoke certain kinds of altered states of consciousness. Specific features of the experience, such as its allegedly ineffable nature, have been discussed as posing challenges to the informed consent process. A growing call for tailored informed consent documents (ICDs) in the psychedelic bioethics literature raises the question of how closely...

A Field-Wide Review and Analysis of Study Materials Used in Psilocybin Trials: Assessment of Two Decades of Research

Psychedelic Medicine January 20, 2025 Marianna Graziosi, Gabrielle Agin-Liebes, Mary P Cosimano et al. 9 citations

Introduction: Serotonergic psychedelics, serotonin 2A receptor agonists such as psilocybin that can result in substantially altered states of consciousness, are used in recreational and research settings. The safety of psychedelic experiences in research settings is supported by controlled physical environments, presence of clinical and medical staff to address emergent issues, screening for...

Adverse Events in Studies of Classic Psychedelics

JAMA Psychiatry September 4, 2024 Marianna Graziosi, Jared T. Hinkle, Sandeep M. Nayak et al. 126 citations

Importance A clear and comprehensive understanding of risks associated with psychedelic-assisted therapy is necessary as investigators extend its application to new populations and indications. Objective To assess adverse events (AEs) associated with classic psychedelics, particularly serious AEs (SAEs) and nonserious AEs (NSAEs) requiring medical or psychiatric evaluation. Data Sources The...

Centering and flourishing: an online intervention study assessing the effects of a Christian contemplative practice on stress-reduction and human flourishing.

BMC Psychol July 1, 2024 Julia S Rohde, Sean P. Goldy, Marianna Graziosi et al. 2 citations

Centering and flourishing: an online intervention study assessing the effects of a Christian contemplative practice on stress-reduction and human flourishing.

Mind the Psychedelic Hype: Characterizing the Risks and Benefits of Psychedelics for Depression

Psychoactives April 16, 2024 Daniel Meling, Rebecca Ehrenkranz, Sandeep M. Nayak et al. 26 citations

Rationale: Psychedelic research re-emerged from a period of suppression into the so-called psychedelic renaissance. In parallel, most media reporting has shifted from the overstatement of the risks of psychedelics to overly positive hype. As the empirical evidence is more equivocal than frequently portrayed, the conclusions about the effectiveness of psychedelics should be considered...

Developing a short form of the Awe Experience Scale (AWE-SF) in psychedelic samples.

PLoS One 2024 Marianna Graziosi, Julia Sarah Rohde, Stephanie Lake et al. 6 citations

This study aimed to develop and validate a short-form version of the AWE-S (AWE-SF) within psychedelic samples, to reduce participant burden while maintaining psychometric integrity. Across five studies, we first replicated the original six-factor structure of the AWE-S through exploratory and confirmatory factor analyses (Study 1), leading to the creation of the 12-item AWE-SF (Study 2-3). We...

Acute Subjective Effects of Psychedelics within and Beyond WEIRD Contexts

Journal of Psychoactive Drugs September 7, 2023 Marianna Graziosi, Manvir Singh, Sandeep M. Nayak et al. 10 citations

ABSTRACT Reports of psychedelic experiences may contain similarities and differences across cultural contexts, but most current characterizations and quantifications of psychedelic experiences come from Western medical and naturalistic settings. In this article, we begin with a brief history of the diversity of psychedelic use in non-Western settings. We then compare and contrast accounts of...

Psychedelics and Psychotherapy: Cognitive-Behavioral Approaches as Default

Frontiers in Psychology May 23, 2022 David B. Yaden, Dylan Earp, Marianna Graziosi et al. 106 citations

The acute subjective effects of psychedelics are responsive to users’ expectations and surroundings (i.e., “set and setting”). Accordingly, a great deal of thought has gone into designing the psychosocial context of psychedelic administration in clinical settings. But what theoretical paradigms inform these considerations about set and setting? Here, we describe several historical, sociological...

Content Analysis of Spiritual Life in Contemporary USA, India, and China

Religions June 12, 2020 Elsa Lau, Clayton H. Mcclintock, Marianna Graziosi et al.

This study investigates the lived-experience of spiritual life in contemporary USA, India, and China. A qualitative coding frame was constructed based on participant responses to open-ended questions regarding spirituality. Qualitative analysis was facilitated by the use of Dedoose, a mixed methods software. The exploratory approach of this study takes on a cross-culturally comparative lens,...