Objectives: Mindfulness has generated considerable interest in the last 2 decades in clinical and research settings. The efficacy of mindfulness has been evaluated for the sexual dysfunctions recognized by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) and other sexual problems, such as compulsive sexual behavior disorder (CSBD), also known as sex addiction or...
Background Cannabis (Δ 9 -THC) is the most commonly consumed illicit drug. The Agricultural Improvement Act of 2018 removed hemp, a strain of Cannabis sativa , as a controlled substance. This law allowed the plant to be processed into its components, which contain <0.3% Δ 9 -THC. As a result, delta-8-tetrahydrocannabinol (Δ 8 -THC), a federally unregulated substance, grew in popularity in 2020....
Introduction: The efficacy of interventions based on mindfulness and compassion has been demonstrated in both clinical and general population, and in different social contexts. These interventions include so-called attentional and constructive meditation practices, respectively. However, there is a third group, known as deconstructive meditation practices, which has not been scientifically...
Methylone is one of the most common synthetic cathinones popularized as a substitute for 3,4-methylenedioxymethamphetamine (MDMA, midomafetamine) owing to its similar effects among users. Both psychostimulants exhibit similar chemistry (i.e., methylone is a β-keto analog of MDMA) and mechanisms of action. Currently, the pharmacology of methylone remains scarcely explored in humans. Herein, we...
Adolescent exposure to cannabinoids as a postnatal environmental insult may increase the risk of psychosis in subjects exposed to perinatal insult, as suggested by the two-hit hypothesis of schizophrenia. Here, we hypothesized that peripubertal Δ9-tetrahydrocannabinol (aTHC) may affect the impact of prenatal methylazoxymethanol acetate (MAM) or perinatal THC (pTHC) exposure in adult rats. We...
Abstract There is increasing clinical interest in the use of psilocybin. There is emerging evidence of the efficacy of psilocybin for the treatment of a range of clinical conditions. Mental health nurses have a unique set of skills for caring for people who are hallucinating. To expand these skills to meet the developing clinical interest in the therapeutic use of psilocybin, it is helpful to...
The potential benefits and deficits of the chemical compound psilocybin, particularly when paired with psychotherapeutic interventions, have been increasingly apparent topics of interest in social, academic, and scientific circles. The unusual nature of psilocybin poses many questions in Western culture. Three of them, which will be discussed in the following review, are (1) What is...
Abstract Impairment in social functioning is a common source of morbidity across many mental health disorders, yet there is a dearth of effective and easily implemented interventions to support social functioning. MDMA/ecstasy and classic psychedelics (psilocybin, LSD, peyote, mescaline) represent two potential treatments for impairments in social functioning, as evidence suggests these...
Abstract N,N‐dimethyltryptamine (DMT) is a psychedelic substance and is being used as a research tool in investigations of the neurobiology behind the human consciousness using different brain imaging techniques. The effects of psychedelics have commonly been studied using electroencephalography (EEG) and have been shown to produce suppression of alpha power and increase in signal diversity....
ABSTRACT Traumatic brain injury (TBI) is an important cause of mortality and morbidity worldwide. Cannabis use disorder and psychosis are rare but serious comorbidities seen after TBI. Recent studies indicate that the use of cannabis for self-medication may increase after TBI. Schizophrenia-like psychosis (SLP) is also seen, generally showing a late and gradual onset after TBI. Especially in...