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Addiction: all studies

Page 417 of 857: studies 4,161 to 4,170 of 8,563, newest first. Back to the addiction overview

Research

Ketamine Evolving Clinical Roles and Potential Effects with Cognitive, Motor and Driving Ability

Neurology International March 28, 2023 Amber N. Edinoff, Saveen Sall, Colby B. Koontz et al. 5 citations

While driving under the influence of drugs, drivers are more likely to be involved in and cause more accidents than drivers who do not drive under the influence. Ketamine is derived from phencyclidine and acts as a noncompetitive antagonist and allosteric modulator of N-methyl-D-aspartate receptors. Ketamine has been used to treat a variety of psychiatric disorders, with the most notable being...

Contribution of serotonin 5-HT2A receptor to antidepressant effect of serotonergic psychedelics

Folia Pharmacologica Japonica March 28, 2023 Daisuke Ibi 1 citation

Major depressive disorder presents a substantial global health burden, and at least 30-40% of patients exhibit treatment resistance to antidepressants. Ketamine, an NMDA receptor antagonist, is used as an anesthetic agent. In 2019, the U.S. Food and Drug Administration (FDA) approved esketamine (the S-enantiomer of ketamine) as a therapeutic agent for treatment-resistant depression; however,...

Experts to Discuss the Ethics of Psychedelics

Psychiatric News March 27, 2023 Terri D’arrigo

Back to table of contents Previous article Next article Annual MeetingFull AccessExperts to Discuss the Ethics of PsychedelicsTerri D'ArrigoTerri D'ArrigoPublished Online:27 Mar 2023https://doi.org/10.1176/appi.pn.2023.04.3.10AbstractA session at APA's Annual Meeting will cover the current state of psychedelics research and offer points to consider in the event of broad psychedelics...

DOI: 10.1176/appi.pn.2023.04.3.10 (opens in new tab) Psilocybin Conversation Legalization Psychotherapist +3

Fear of missing out (FOMO) associates with reduced cortical thickness in core regions of the posterior default mode network and higher levels of problematic smartphone and social media use.

Addictive Behaviors March 25, 2023 Lan Wang, Xinqi Zhou, Xinwei Song et al.

Background and aims: Fear of missing out (FOMO) promotes the desire or urge to stay continuously connected with a social reference group and updated on their activities, which may result in escalating and potentially addictive smartphone and social media use. The present study aimed to determine whether the neurobiological basis of FOMO encompasses core regions of the reward circuitry or social...

Social reappraisal of emotions is linked with the social presence effect in the default mode network

Frontiers in Psychiatry March 23, 2023 Xiyao Xie, Teresa Bertram, Saša Zorjan et al.

IntroductionSocial reappraisal, during which one person deliberately tries to regulate another’s emotions, is a powerful cognitive form of social emotion regulation, crucial for both daily life and psychotherapy. The neural underpinnings of social reappraisal include activity in the default mode network (DMN), but it is unclear how social processes influence the DMN and thereby social...

DOI: 10.3389/fpsyt.2023.1128916 (opens in new tab) Full text (opens in new tab) Default mode network Social reappraisal Social support Social emotion regulation +2

Yale Program for Psychedelic Science (YPPS) Manual for Psilocybin Combined with Non-Directive Support in the Treatment of OCD

March 17, 2023 Terence H. W. Ching, Rachael Grazioplene, Christopher Pittenger et al. 6 citations preprint

The Yale Program for Psychedelic Science (YPPS) supports a multi-disciplinary research community dedicated to investigating the effects of psychedelic substances on brain function, cognition, and behavior, including their therapeutic potential in treating neuropsychiatric conditions. In support of this mission, YPPS is testing the safety and efficacy of psilocybin, administered in conjunction...

Direct Effects of Cannabis Intoxication on Motivations for Softer and Harder Drug Use: An Experimental Approach to the Gateway Hypothesis

Cannabis and Cannabinoid Research March 16, 2023 Claire M. Gorey, Emese Kroon, N. Runia et al.

Aims: This study experimentally tested whether there is a gateway-type effect of cannabis administration on tobacco and cocaine motivation and whether motivational responses predicted use 6 months later. Methods: A 2 (condition: active cannabis vs. placebo joint)×3 (substance stimulus type: tobacco, cannabis, and cocaine) factor within-subjects design for both implicit and explicit motivation....

Diferencias y estabilidad diagnóstica entre trastornos psicóticos inducidos por sustancias y trastornos psicóticos no inducidos

Adicciones March 15, 2023 Julia Cambra Almerge, Sergio Sánchez-Romero, F. Árias 3 citations

Several hypotheses have been proposed to explain the comorbidity between psychotic disorders and substance use, one of them being the capacity of some to induce psychotic symptoms, although the transition from psychotic episodes induced by substances to schizophrenia has been less studied. In this study, differential variables between patients with induced and non-induced psychosis are...

Exploring psilocybin-assisted psychotherapy in the treatment of methamphetamine use disorder

Frontiers in Psychiatry March 14, 2023 Jonathan Brett, Elizabeth Knock, Paul Liknaitzky et al. 16 citations

Methamphetamine use disorder is a chronic relapsing condition associated with substantial mental, physical, and social harms and increasing rates of mortality. Contingency management and psychotherapy interventions are the mainstays of treatment but are modestly effective with high relapse rates, while pharmacological treatments have shown little to no efficacy. Psilocybin-assisted...

DOI: 10.3389/fpsyt.2023.1123424 (opens in new tab) Psilocybin Methamphetamine Psychotherapist Hallucinogen +2

Should Psychedelic Drugs Be Offered as a Treatment for Mental Illness?

Journal of Humanities Arts and Social Science March 13, 2023 Ruoqi Zhang

Psychedelics are becoming increasingly popular as an entry point into difficult- to-treat psychiatric illnesses and a supplement to existing treatments. However, many people view these substances with caution due to increased incidents where they've been used illegally in unsupervised settings. This paper argues that adding psychedelics to the treatment of mental illness can be beneficial for...