The International Journal of Neuropsychopharmacology
September 1, 2026
Christopher Sheridan, Guillaume Thuery, K Brennan et al.
Abstract Background Serotonergic psychedelics have recently re-emerged as promising therapeutic agents in psychiatry, showing positive outcomes in clinical trials for treatment-resistant depression, major depression, and PTSD. However, their effects on the immune system are poorly characterized. It remains unclear whether these compounds exert immunomodulatory effects that contribute to their...
The International Journal of Neuropsychopharmacology
September 1, 2026
Jessica Mingardi, Stefano Spinosa, Noemi Nicosia et al.
Abstract Background Stress is a recognized risk factor for developmental and adult psychiatric disorders. Indeed, stressful events, particularly during the first phases of life, such as trauma, neglect or abuse, have been associated with increased psychiatric risk over the course of a lifetime, although with some sex-differences. Indeed, the biological sex shapes the stress response impacting...
International Journal of Human-Computer Studies
September 1, 2026
Arianna Boldi, Kutub Gandhi, Alexandra To et al.
Research on psychoactive substance use during video game play has traditionally adopted a medical lens, focusing on the addictive potential of licit and illicit drugs and their pathological impacts on players. This framing highlights negative outcomes of the co-occurrence between excessive gaming and substance use, leaving the motivations, meanings, and perceptions that players themselves...
Human Psychopharmacology: Clinical and Experimental
September 1, 2026
José Norberto Vásquez-Bonilla
OBJECTIVE: This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti-inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices, and pharmacological interactions. METHODS: A...
Zenodo (CERN European Organization for Nuclear Research)
September 1, 2026
Aissa Walid Benarous
preprint
This paper takes as its starting point a recurring feature of Qur’anic vocabulary: verses that consistentlyassociate the faculties of reasoning (‘aql) and understanding with the heart (qalb), and verses that as-sociate genuine, efficacious hearing (sam‘) with consciousness or wakefulness (wa‘y), often placingthe two faculties in relations of equivalence, exchange, or causal dependence rather...
Zenodo (CERN European Organization for Nuclear Research)
September 1, 2026
Clifton Bacon
preprint
A foundational problem in physics remains unresolved: the role of the conscious observer in quantum measurement. This paper develops a theoretical framework, the Silence Paradigm, that generates testable predictions bearing on that problem. It treats the observer's state of consciousness as a controlled experimental variable rather than as a philosophical assumption, and asks whether the...
Nature Communications
September 1, 2026
Maxime Veleanu, Louise E. Schuberth, Antje Kilias et al.
The pathophysiology of depression involves multiple biological processes, including circuit dysfunction and impaired neuroplasticity, yet an integrative view linking these processes remains elusive. Here, we identify a convergent circuit for antidepressant response and plasticity modulation. We demonstrate that chemogenetic activation of the infralimbic cortex (IL) exerts rapid...
Dhammacakka Journal of Buddhism and Applied Buddhism
September 1, 2026
Ven. Silacari
Vipassanā1 meditation is central to modern Theravāda Buddhism, especially in Myanmar has been one of the most influential places in its recent development and international transmission. Although previous studies have examined individual teachers, specific techniques, or modern mindfulness, very few studies connect the historical growth of Myanmar Vipassanā with a structured comparison of its...
Zenodo (CERN European Organization for Nuclear Research)
September 1, 2026
Zen Revista, 10 Philosophy
preprint
This article presents a narrative review of Phenomenology and the First-Person Point of View in the context of Philosophy. The literature on this topic has expanded substantially over recent decades, yet it remains fragmented across subfields, methods, and national research traditions. Drawing on an interpretive synthesis of representative contributions, the review reconstructs the historical...
Zenodo (CERN European Organization for Nuclear Research)
September 1, 2026
Zen Revista, 10 Philosophy
preprint
This article presents a narrative review of Phenomenology and the First-Person Point of View in the context of Philosophy. The literature on this topic has expanded substantially over recent decades, yet it remains fragmented across subfields, methods, and national research traditions. Drawing on an interpretive synthesis of representative contributions, the review reconstructs the historical...