The International Journal of Neuropsychopharmacology
September 9, 2026
Noemi Nicosia, Jessica Mingardi, G Terribile et al.
Abstract Background Chronic stress is a key risk factor for major depressive disorder (MDD), one of the leading causes of disability worldwide1. Despite available pharmacological therapies, treatment-resistant depression (TRD) remains a clinical challenge. Hallucinogens such as ketamine and serotonergic psychedelics including psilocybin and lysergic acid diethylamide (LSD)2 show rapid...
The International Journal of Neuropsychopharmacology
September 1, 2026
Jessica Mingardi, Stefano Spinosa, Noemi Nicosia et al.
Abstract Background Stress is a recognized risk factor for developmental and adult psychiatric disorders. Indeed, stressful events, particularly during the first phases of life, such as trauma, neglect or abuse, have been associated with increased psychiatric risk over the course of a lifetime, although with some sex-differences. Indeed, the biological sex shapes the stress response impacting...
Pharmacological Research
August 26, 2026
Mattia Giovenzana, Noemi Nicosia, Stefano Spinosa et al.
Neurodevelopmental disorders (NDDs) comprise a heterogeneous group of conditions arising from altered brain development and leading to impairments in social, cognitive, emotional, and motor domains. Clinical manifestations are highly variable in severity and symptom profile, reflecting the complex and multifactorial etiology of NDDs. Available treatments are limited to early behavioral...
The International Journal of Neuropsychopharmacology
February 12, 2025
*Danilo De Gregorio, Carolina Giulia Ferroni, Noemi Nicosia et al.
Abstract Introduction Alcohol use disorder (AUD) is a major problem that causes significant health and social problem. Pharmacological treatments for AUD are limited in their effectiveness, and new drugs are required (ref). Recently, the potential use of psychedelics as novel therapies in treating mental diseases has come to the forefront in psychiatry. For instance, lysergic acid diethylamide...