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Addiction: all studies

Page 108 of 855: studies 1,071 to 1,080 of 8,547, newest first. Back to the addiction overview

Research

The Ownership Answer: What It Is Like

Zenodo (CERN European Organization for Nuclear Research) October 24, 2026 Victor Wyld preprint

David Chalmers asks why the performance of physical functions is accompanied by experience. This paper answers: Ownership. Its argument has two tiers. The first holds that he argues for conceptual separability and draws from it more than it supports. His evidence shows that experience and physical process go together. That new fundamental laws, or a further phenomenal nature underlying the...

Mel-frequency cepstral coefficients and spectral features directly drive micro-level autonomic reflexes during brief respiration practices

October 23, 2026 Jung-tzu Chang, Zai‐Fu Yao preprint

While digital health platforms increasingly deliver guided mindful breathing interventions via audio, the specific acoustic properties of the guidance are fundamentally ignored as potential active ingredients. This within-subject study implemented an unprecedented high-density experimental design to investigate how distinct, computationally engineered acoustic features (e.g., pitch,...

A ketamine derivative exerts enhanced antidepressant effects via adenosine signaling.

Science China. Life sciences October 22, 2026 Na Wang, Chenyu Yue, Xiaofeng Fan et al.

Ketamine exerts rapid antidepressant effects but is limited by dissociative and abuse-related side effects, highlighting the need for safer alternatives. Here, we identify 3C-DCK, a rationally designed ketamine derivative, through adenosine dynamics in the medial prefrontal cortex (mPFC). Using the GRABAdo1.0 sensor, we show that 3C-DCK elicits more potent and sustained extracellular adenosine...

Treatment Response Following Repeated Low-Dose Oral Ketamine in Adults with Chronic Suicidality

University of the Sunshine Coast October 22, 2026 Cyrana C. Gallay

Suicide is an urgent public health concern and a leading cause of death, globally. Chronic suicidality may be described as persistent or recurrent suicidal ideation presenting over periods of months to years. While suicidality is associated with a complex range of proximal and distal risk factors, there is no single set of clinical features accurately able to predict development. Limited...

Effects of Social Isolation on the Behavior of Wistar Rats Subjected to a Ketamine-Induced Model of Schizophrenia

Bratislavské lekárske listy/Bratislava medical journal October 22, 2026 Isabela Hubbe, Ana Luísa S. Ferreira, Nicole Luiza Rizzotto et al.

Abstract This study aimed to evaluate the impact of chronic social isolation on the behavioral profile of male and female Wistar rats within a ketamine (Ket)-induced model of schizophrenia. A total of 144 adult Wistar rats (male and female) were divided into four experimental groups per sex: (1) Socialized + Saline (Sal) (Control group); (2) Socialized + Ket; (3) Isolated + Sal (Isolated...

Digital Mediation, Selfhood, and Hybrid Agency: A Minimal Three-Dimensional Framework

Research Square October 22, 2026 Saida Agzamkhodjayeva preprint

Abstract Claims that digital technologies blur the boundaries of consciousness and personal identity often collapse several distinct philosophical questions. This article develops a minimal three-dimensional framework of digital mediation that distinguishes cognitive integration, self-representational mediation, and agential distribution. Unlike existing multidimensional accounts that remain...

Neurospirituality Reappraised: Brain Mechanisms of Transcendent Experience and Beyond

PsyArXiv Preprints October 22, 2026 preprint

Background: Subjective experiences featuring altered self-awareness, temporal perception, or spatial boundaries—termed Non-Ordinary Experiences (NOEs)—occur across clinical neurology, psychiatry, and psychedelic medicine, including in insular ecstatic seizures, meditation, breathwork, hypnosis, and psychedelic therapy. Objective: To synthesize neurobiological and clinical literature on NOEs for...

Realism, Idealism, and the Paradox of Subjectivity in Transcendental Phenomenology

European Journal of Philosophy October 22, 2026 Tyeson Davies-Barton

Abstract This article examines the significance of what Edmund Husserl calls “the paradox of human subjectivity” for the metaphysical realism‐idealism debate in transcendental phenomenology. I distinguish two plausible interpretations of the paradox that are relevant to this debate. I term the first a vicious circle of mutual dependence: the world is characterized as being ontologically...

Beyond Skin and Skull: A Dispositional Approach to the Extended Mind

Topoi October 22, 2026 Paul Richard Smart

Abstract Debates about the extended mind and extended cognition typically focus on the boundaries of cognitive processes and the mechanisms responsible for their realization. This paper develops a different perspective, one that foregrounds the role of dispositional properties such as beliefs, capacities, and abilities. According to the dispositional hypothesis, cases of cognitive extension...

චරය හඩගසවමහල බදධ උපදශනය භවතය ගණතමක අධයයනයක -The Application of Buddhist Counselling for Character Modification: A Qualitative Study

Journal of postgraduate institute of pali and buddhist studies. October 21, 2026 Ven. Kumbukandana Rewatha

This study with aim to identify the usage of Buddhist Counselling for behavior modification applied the qualitative research approach, 12 male counselors and 8 female counselors were selected using a purposive sampling method. Data were collected through semi-structured interviews and qualitatively analyzed using thematic analysis. According to the findings, criteria such as criteria for...