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Mindfulness-based cognitive therapy for depressed individuals improves suppression of irrelevant mental-sets

Jonathan Greenberg, Benjamin G. Shapero, David Mischoulon, Sara W. Lazar

European Archives of Psychiatry and Clinical Neuroscience November 9, 2016 DOI: 10.1007/s00406-016-0746-x (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Non-randomized controlled trial Peer reviewed
Sample size 40
Population Depressed individuals
Intervention Mindfulness-based cognitive therapy
Topics Meditation
Keywords Mindfulness-based cognitive therapy Cognition Depression economics Clinical psychology Psychotherapist Mental health Cognitive flexibility
Citations 17
Key findings MBCT plus treatment-as-usual improved suppression of irrelevant mental sets, and these improvements were associated with reduced depression scores.

Abstract

An impaired ability to suppress currently irrelevant mental-sets is a key cognitive deficit in depression. Mindfulness-based cognitive therapy (MBCT) was specifically designed to help depressed individuals avoid getting caught in such irrelevant mental-sets. In the current study, a group assigned to MBCT plus treatment-as-usual (n = 22) exhibited significantly lower depression scores and greater improvements in irrelevant mental-set suppression compared to a wait-list plus treatment-as-usual (n = 18) group. Improvements in mental-set-suppression were associated with improvements in depression scores. Results provide the first evidence that MBCT can improve suppression of irrelevant mental-sets and that such improvements are associated with depressive alleviation.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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