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Treatment-resistant Depressed Patients Show a Good Response to Mindfulness-based Cognitive Therapy

Maura Kenny, J. Mark G. Williams

FOCUS The Journal of Lifelong Learning in Psychiatry January 1, 2010 DOI: 10.1176/foc.8.1.foc120 (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

Mindfulness-based Cognitive Therapy (MBCT), originally designed to prevent relapse of major depression, was tested in a clinical audit with patients who were currently actively depressed and had not fully responded to standard treatments. The therapy was acceptable to these patients and led to an improvement in depression scores, with a pre-post effect size of 1.04. A significant proportion of patients returned to normal or near-normal levels of mood.

Study at a glance

Characteristics Clinical audit Peer reviewed
Population Patients who were currently actively depressed and had not responded fully to standard treatments
Intervention Mindfulness-based Cognitive Therapy
Topics Meditation
Keywords Mindfulness-based cognitive therapy Cognition Depression economics Mood Clinical psychology
Citations 1
Key finding MBCT was acceptable to actively depressed patients and resulted in an improvement in depression scores, with a significant proportion returning to normal or near-normal mood.

Abstract

Mindfulness-based Cognitive Therapy (MBCT) is a class-based programme designed for use in the prevention of relapse of major depression. Its aim is to teach participants to disengage from those cognitive processes that may render them vulnerable to future episodes. These same cognitive processes are also known to maintain depression once established, hence a clinical audit was conducted to explore the use of MBCT in patients who were currently actively depressed, and who had not responded fully to standard treatments. The study showed that it was acceptable to these patients and resulted in an improvement in depression scores (pre-post Effect Size=1.04), with a significant proportion of patients returning to normal or near-normal levels of mood. (Reprinted with permission from Behaviour Research and Therapy 2007; 45:617–625)

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