Effects of Mescaline in Laboratory Animals and Influence of Ataraxics on Mescaline-Response
F. M. Sturtevant, Victor A. Drill
Experimental Biology and Medicine June 1, 1956 DOI: 10.3181/00379727-92-22485 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Experimental study Peer reviewed |
|---|---|
| Population | Dogs and cats |
| Interventions | Mescaline Chlorpromazine Reserpine Azacyclonol |
| Topics | Mescaline |
| Keywords | Cats Reserpine Chlorpromazine Catatonia Pharmacology Plant-based medicinal research |
| Citations | 15 |
| Key findings | Mescaline-induced acute autonomic effects and catatonia in dogs and cats appeared to be altered or prevented by pretreatment with chlorpromazine, reserpine, and azacyclonol. |
Abstract
Mescaline, injected intravenously and intraperitoneally into dogs and cats and into the lateral ventricle of the brain of cats, produced acute autonomic effects followed by catatonia. These responses appeared to be altered or prevented by pretreatment with the ataraxic agents chlorpromazine, reserpine, and azacyclonol.
Comparable studies
Other experimental studies on mescaline, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds Rabbit lung | 1961 | Experimental study | |
| PSYCHOTOMIMETICS, CLINICAL AND THEORETICAL CONSIDERATIONS: HARMINE, WIN-2299 AND NALLINE Schizophrenic patients | 1957 | Experimental study | |
| Phencyclidine, Lysergic Acid Diethylamide, and Mescaline: Cerebral Artery Spasms and Hallucinogenic Activity Isolated basilar and middle cerebral arteries | 1981 | Experimental study | |
| Acquired and Crossed Tolerance to Mescaline, LSD-25, and BOL-148 | 1959 | Experimental study | |
| Effects of Hallucinogenic and Tranquilizing Drugs on Serotonin Evoked Uterine Contractions. Uterus of spayed rat | 1956 | Experimental study |
Citations in the library
Cited by 2
- A STEREOTYPED RESPONSE INDUCED BY MESCALINE IN MICE AS A MEANS OF INVESTIGATING THE PROPERTIES OF DRUGS ACTING ON THE CNS Journal of Pharmacy and Pharmacology September 1, 1958
- Development of tolerance to the antinociceptive effect of mescaline intraventricularly administered to rabbits Psychopharmacology 1976