medRxiv
July 4, 2026
Marco Zierhut, Max Alt, Inge Maria Hahne et al.
Abstract Background Negative symptoms in schizophrenia spectrum disorders (SSD) remain insufficiently treated and require novel therapeutic approaches. Oxytocin may improve negative symptoms, although its effects appear highly context-dependent according to the social salience hypothesis. We conducted a randomized, triple-blind, placebo-controlled pilot study combining intranasal oxytocin with...
Schizophrenia
April 30, 2026
Marco Zierhut, S. Koop, N. Bergmann et al.
This study investigates changes in stress parameters in individuals with schizophrenia spectrum disorders participating in mindfulness-based group therapy (MBGT). N = 45 participants were randomised to MBGT or Treatment as Usual over four weeks. Before and after each session, psychological and biological stress markers by self-rating scales and cortisol saliva samples were assessed in the...
Frontiers in Psychology
2026
Niklas Bergmann, Ingmar Conell, Inge Hahne et al.
Cognitive fusion, a key construct in Acceptance and Commitment Therapy (ACT), describes the overidentification with internal thoughts that compromises psychological flexibility and contributes to maladaptive emotion regulation. Cognitive defusion techniques aim to reduce this entanglement, promoting adaptive functioning and improved mental health. This study examined the psychometric properties...
Scientific Reports
September 23, 2025
Daniel Heppt, Niklas Bergmann, Ingmar Conell et al.
The present article explores the relationship between mindfulness meditation and personality. Based on a substantial body of research, mindfulness has been shown to have significant associations with personality. Recent research suggests that mindfulness meditation may influence personality traits in accordance with the Five Factor Personality Model. To examine this, we investigated whether...
Scientific Reports
June 4, 2025
Inge Hahne, Julia Segerer, Marco Zierhut et al.
3 citations
The effectiveness of mindfulness-based interventions (MBIs) in enhancing mental well-being and reducing positive, negative, and depressive symptoms in schizophrenia spectrum disorders (SSD) has been increasingly supported by evidence. However, the underlying mechanisms of MBIs require further examination. Psychological flexibility (PF), typically assessed through cognitive fusion, has been...
Schizophrenia Bulletin
November 16, 2024
Inge Hahne, Marco Zierhut, Niklas Bergmann et al.
3 citations
The efficacy of yoga as an adjunctive treatment for schizophrenia spectrum disorders (SSD) has garnered interest. While yoga may positively influence various symptom domains, further investigation is needed due to the limited number, quality, and generalizability of studies. This study assessed the feasibility and acceptability (primary outcome) of a yoga-based group intervention (YoGI)...
European Psychiatry
November 17, 2023
Kerem Böge, Inge Hahne, Niklas Bergmann et al.
Introduction The therapeutic effectiveness of mindfulness-based interventions (MBIs) has been shown for various mental disorders. However, for schizophrenia spectrum disorders (SSD), only a few trials have been conducted, mostly in outpatient settings. Objectives This study aimed to investigate feasibility, acceptability, and preliminary effectiveness of a four-week mindfulness-based group...
Frontiers in Psychology
September 3, 2021
Niklas Bergmann, Eric Hahn, Inge Hahne et al.
Background: Schizophrenia spectrum disorders (SSD) are frequently accompanied by comorbid depressive and anxiety symptoms, as well as impaired quality of life (QoL). A growing body of evidence has demonstrated the relevance of mindfulness for SSD in recent years. The study examined the association between mindfulness, depression, anxiety, and QoL.Materials and Methods: A total of 83...