Response of cluster headache to psilocybin and LSD
R. Andrew Sewell, John H. Halpern, Harrison G. Pope
Neurology June 26, 2006 DOI: 10.1212/01.wnl.0000219761.05466.43 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Qualitative study Peer reviewed |
|---|---|
| Sample size | 53 |
| Population | Cluster headache patients who used psilocybin or LSD |
| Interventions | Psilocybin Lysergic acid diethylamide (LSD) |
| Topics | LSD Psilocybin |
| Keywords | Ipilimumab Nivolumab Demographics Adverse effect Retrospective cohort study Complete response Oncology Cancer |
| Citations | 259 |
| Key findings | Psilocybin and LSD were reported by most users to abort attacks, terminate cluster periods, and extend remission periods. |
Abstract
The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on the effects of psilocybin and LSD on cluster headache may be warranted.