Default mode network connectivity in stable vs progressive mild cognitive impairment
Neurology January 13, 2011 Jeffrey R. Petrella, Forrest Sheldon, Steven E. Prince et al. 291 citations
OBJECTIVE: Dysfunction of the default mode network (DMN) has been identified in prior cross-sectional fMRI studies of Alzheimer disease (AD) and mild cognitive impairment (MCI); however, no studies have examined its utility in predicting future cognitive decline. METHODS: fMRI scans during a face-name memory task were acquired from a cohort of 68 subjects (25 normal control, 31 MCI, and 12 AD)....