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PLoS One

ISSN 1932-6203

260 papers in the library · 13,923 citations · publishing 2008-2026

Papers

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The effectiveness of mindfulness training in improving medical students' stress, depression, and anxiety.

PLoS One 2023 Ahmed M Alzahrani, Ahmed Hakami, Ahmad Alhadi et al. 31 citations

There is growing interest in Mindfulness-based Stress Reduction (MBSR) program to combat mental distress in medical students. In Saudi Arabia, literature is insufficient about MBSR and its effectiveness. This study aims to measure the effectiveness of MBSR in improving mindful state, stress, anxiety, and depression in medical students. Also, the study explores the association between the...

Effects of a mindfulness-based intervention and a health self-management programme on psychological well-being in older adults with subjective cognitive decline: Secondary analyses from the SCD-Well randomised clinical trial.

PLoS One 2023 Marco Schlosser, Harriet Demnitz-King, Thorsten Barnhofer et al. 13 citations

Older adults with subjective cognitive decline (SCD) recruited from memory clinics have an increased risk of developing dementia and regularly experience reduced psychological well-being related to memory concerns and fear of dementia. Research on improving well-being in SCD is limited and lacks non-pharmacological approaches. We investigated whether mindfulness-based and health education...

The mechanism and effectiveness of mindfulness-based intervention for reducing the psychological distress of parents of children with autism spectrum disorder: A protocol of randomized control trial of ecological momentary intervention and assessment.

PLoS One 2023 Qi Wang, Siu-Man Ng, Xiaochen Zhou 9 citations

Existing studies have unequivocally demonstrated that parents of children with autism spectrum disorder (ASD) experience various stressful daily life events and suffer from psychological distress. Mindfulness level is found to be an effective buffer between parents' appraisal of stress life events and psychological distress. However, the mechanism behind the function of mindfulness is unclear,...

An 18-month meditation training selectively improves psychological well-being in older adults: A secondary analysis of a randomised controlled trial.

PLoS One 2023 Marco Schlosser, Olga Klimecki, Fabienne Collette et al. 6 citations

As the world population is ageing, it is vital to understand how older adults can maintain and deepen their psychological well-being as they are confronted with the unique challenges of ageing in a complex world. Theoretical work has highlighted the promising role of intentional mental training such as meditation practice for enhancing human flourishing. However, meditation-based randomised...

Increasing autobiographical memory specificity: Using kindness meditation to impact features of memory retrieval.

PLoS One 2023 Amanda Lathan, Barbara Dritschel 5 citations

Individuals with a history of depression have an increased risk for future episodes. This risk has been linked with impaired features of autobiographical memory retrieval that remain when depressive symptoms abate, including memory specificity, remoteness, valence, and vantage perspective. Rumination has been shown to influence these impairments and can be reduced via compassion training. We...

Interventions combining mindfulness training with non-invasive brain stimulation and their impact on mental health outcomes: Protocol for a systematic review and meta-analysis of randomized controlled trials.

PLoS One 2023 Anastasia Demina, Benjamin Petit, Vincent Meille et al. 2 citations

Mindfulness training programs and non-invasive brain stimulation are both evidence-based interventions that have applications in mental health disorders. While both have showed promising results on a range of symptoms related to mental health, their combination has more recently grabbed the attention of researchers. There is a theoretical framework for their synergistic effects, and these...

Doing what matters in times of stress: No-nonsense meditation and occupational well-being in COVID-19.

PLoS One 2023 Justine Van de Velde, Katia Levecque, Bert Weijters et al. 1 citation

While the COVID-19 pandemic challenged the general public's health and well-being, it exacerbated the pre-existing well-being issues in the educational sector in many countries. Mindfulness-based interventions are often applied to protect and promote occupational well-being. To investigate how the well-being benefits of these interventions arise, we selected one accessible technique that is...

Improving the mental health and well-being of healthcare providers using the transcendental meditation technique during the COVID-19 pandemic: A parallel population study.

PLoS One 2023 Mark S Nestor, Alec Lawson, Daniel Fischer

Frontline Healthcare provider (HCP) burnout has dramatically increased due to the COVID 19 pandemic. Hospitals are supporting wellness programs and techniques to reduce burnout including the Transcendental Meditation (TM) technique. This study evaluated the use of TM on HCP symptoms of stress, burnout and wellness. A total of 65 HCPs at three South Florida hospitals were recruited and...

Supporting antidepressant discontinuation using mindfulness plus monitoring versus monitoring alone: A cluster randomized trial in general practice.

PLoS One 2023 Marloes J. Huijbers, Carolien Wentink, Peter L B J Lucassen et al.

Discontinuing antidepressant medication (ADM) can be challenging for patients and clinicians. In the current study we investigated if Mindfulness-Based Cognitive Therapy (MBCT) added to supported protocolized discontinuation (SPD) is more effective than SPD alone to help patients discontinue ADM. This study describes a prospective, cluster-randomized controlled trial (completed). From 151...

Application of machine learning and complex network measures to an EEG dataset from ayahuasca experiments

PLoS One December 16, 2022 Caroline L. Alves, Rubens Gisbert Cury, Kirstin Roster et al. 13 citations

Ayahuasca is a blend of Amazonian plants that has been used for traditional medicine by the inhabitants of this region for hundreds of years. Furthermore, this plant has been demonstrated to be a viable therapy for a variety of neurological and mental diseases. EEG experiments have found specific brain regions that changed significantly due to ayahuasca. Here, we used an EEG dataset to...

“A sense of the bigger picture:” A qualitative analysis of follow-up interviews with people with bipolar disorder who self-reported psilocybin use

PLoS One December 14, 2022 Meghan DellaCrosse, Mollie Pleet, Emma Morton et al. 28 citations

Objectives People with bipolar disorder (BD) spend more time depressed than manic/hypomanic, and depression is associated with greater impairments in psychosocial functioning and quality of life than mania/hypomania. Emerging evidence suggests psilocybin, the psychoactive compound in “magic mushrooms,” is a promising treatment for unipolar depression. Clinical trials of psilocybin therapy have...

The impact of a brief mindfulness training on interoception: A randomized controlled trial

PLoS One September 7, 2022 Geissy Lainny de Lima-Araújo, Geovan Menezes de Sousa, Thatiane Aparecida Mendes et al. 64 citations

Interoception is a collection of different representations of signals originating within the body. The way of perceiving these signals seems to be related to both emotion regulation and dysregulation, and its dysfunction is implicated across a variety of affective disorders. There is a growing body of research investigating the relationship between mindfulness meditation practices and...

Comparison of psychedelic and near-death or other non-ordinary experiences in changing attitudes about death and dying

PLoS One August 24, 2022 Mary M. Sweeney, Sandeep M. Nayak, Ethan Hurwitz et al. 60 citations

Both psychedelic drug experiences and near-death experiences can occasion changes in perspectives on death and dying, but there have been few direct comparisons of these phenomena. This study directly compared psychedelic occasioned and non-drug experiences which altered individuals’ beliefs about death. Individuals who reported an experience that altered their beliefs about death occasioned by...

The effects of mindfulness-based interventions on symptoms of depression, anxiety, and cancer-related fatigue in oncology patients: A systematic review and meta-analysis

PLoS One July 14, 2022 Ellentika Chayadi, N. Baes, L. Kiropoulos

Objective Mindfulness-based interventions (MBIs) are increasingly being integrated into oncological treatment to mitigate psychological distress and promote emotional and physical well-being. This review aims to provide the most recent evaluation of Mindfulness-Based Stress Reduction (MBSR), Mindfulness-Based Cognitive Therapy (MBCT), and Mindfulness-Based Cancer Recovery (MBCR) treatments, in...

Constructive episodic simulation in dreams

PLoS One March 22, 2022 Erin J. Wamsley 22 citations

Memories of the past help us adaptively respond to similar situations in the future. Originally described by Schacter & Addis in 2007, the "constructive episodic simulation" hypothesis proposes that waking thought combines fragments of various past episodes into imagined simulations of events that may occur in the future. This same framework may be useful for understanding the function of...

Phenomenological assessment of psychedelics induced experiences: Translation and validation of the German Challenging Experience Questionnaire (CEQ) and Ego-Dissolution Inventory (EDI)

PLoS One March 16, 2022 Katharina Dworatzyk, Tallulah Jansen, Timo Torsten Schmidt 19 citations

Several measures have been designed to assess subjective experiences induced by psychedelic substances or other mind-altering drugs as well as non-pharmacological methods. Recently, two self-report questionnaires have been introduced to measure acute adverse effects following psilocybin ingestion and the phenomenon of ego-dissolution associated with the use of psychedelics, respectively. The...

Updated cost-effectiveness of MDMA-assisted therapy for the treatment of posttraumatic stress disorder in the United States: Findings from a phase 3 trial

PLoS One February 25, 2022 Elliot Marseille, Jennifer Mitchell, James G. Kahn 49 citations

Background Severe posttraumatic stress disorder (PTSD) is a prevalent and debilitating condition in the United States. and globally. Using pooled efficacy data from six phase 2 trials, therapy using 3,4-methylenedioxymethamphetamine (MDMA) appeared cost-saving from a payer’s perspective. This study updates the cost-effectiveness analysis of this novel therapy using data from a new phase 3...

Lucid dreaming increased during the COVID-19 pandemic: An online survey.

PLoS One 2022 P Kelly, Tainá Macêdo, T Felipe et al. 3 citations

The COVID-19 pandemic changed people's lives all over the world. While anxiety and stress decreased sleep quality for most people, an increase in total sleep time was also observed in certain cohorts. Dream recall frequency also increased, especially for nightmares. However, to date, there are no consistent reports focusing on pandemic-related changes in lucid dreaming, a state during which...

A single-arm open-label pilot study of brief mindfulness meditation to control impulsivity in Parkinson's disease.

PLoS One 2022 Jinsoo Koh, Maiko Takahashi, Yasuhiko Ohmae et al.

Impulse control disorders are detrimental neuropsychiatric symptoms of Parkinson's disease. Increased impulsivity is a predisposing factor for impulse control disorders and should therefore be controlled. Recently, mindfulness meditation as a non-drug therapy has been reported to be useful in improving neuropsychiatric symptoms, such as impulsivity. We performed a prospective single-arm,...

Adverse or therapeutic? A mixed-methods study investigating adverse effects of Mindfulness-Based Cognitive Therapy in bipolar disorder.

PLoS One December 2, 2021 Imke Hanssen, Vera Scheepbouwer, Marloes J. Huijbers et al. 12 citations

BackgroundMindfulness-Based Interventions (MBIs) are widely used in clinical and non-clinical populations, but little attention has been given to potential adverse effects (AEs).AimsThis study aimed to gain insight in the prevalence and course of AEs during Mindfulness-Based Cognitive Therapy (MBCT) for patients with bipolar disorder (BD).MethodThe current mixed-methods study was conducted as...

Does ±3,4-methylenedioxymethamphetamine (ecstasy) induce subjective feelings of social connection in humans? A multilevel meta-analysis

PLoS One October 25, 2021 Annie Regan, Seth Margolis, Harriet de Wit et al. 18 citations

3,4-Methylenedioxymethamphetamine (MDMA) is a psychostimulant known for producing positive subjective effects and for enhancing social functioning and social connection in both clinical and recreational settings. Over the past two decades, scientists have begun to study the psychological effects of MDMA through rigorous placebo-controlled experimental work. However, most existing studies have...

Dreaming of the sleep lab

PLoS One October 6, 2021 Claudia Picard-Deland, Tore Nielsen, Michelle Carr 27 citations

The phenomenon of dreaming about the laboratory when participating in a sleep study is common. The content of such dreams draws upon episodic memory fragments of the participant's lab experience, generally, experimenters, electrodes, the lab setting, and experimental tasks. However, as common as such dreams are, they have rarely been given a thorough quantitative or qualitative treatment. Here...

Altered states phenomena induced by visual flicker light stimulation

PLoS One July 1, 2021 Marie Therese Bartossek, Johanna Kemmerer, Timo Torsten Schmidt 43 citations

Flicker light stimulation can induce short-term alterations in consciousness including hallucinatory color perception and geometric patterns. In the study at hand, the subjective experiences during 3 Hz and 10 Hz stroboscopic light stimulation of the closed eyes were assessed. In a within-subjects design (N = 24), we applied the Positive and Negative Affect Schedule (mood state), time...