Frontiers in Psychiatry
2025
Meng-Han Zhang, Yi-Fan Wang, Juan Li et al.
Catatonia is a rare but potentially life-threatening psycho-motor syndrome. It is mainly manifested as decreased activities, or excessive and specific activities, such as stupor, agitation and defiance. Catatonia can appear in various diseases and the diagnosis and treatment of depressive catatonia are often delayed. As an N-methyl-D-aspartate (NMDA) receptor antagonist, esketamine shows...
Frontiers in Psychiatry
2025
Kyndra Purcell
Bipolar II disorder is traditionally understood as a condition of mood dysregulation, yet beneath its psychological manifestations lies a physiological rhythm often overlooked: the regulation of the autonomic nervous system. This perspective proposes that while bipolar II is not caused by a dysregulated nervous system, its course-and particularly the depth and duration of depressive episodes-is...
Frontiers in Psychiatry
2025
Valerio Ricci, Domenico de Berardis, Giovanni Martinotti et al.
Cannabis use represents a significant environmental risk factor for psychotic disorders, with emerging evidence suggesting complex interactions between cannabinoid exposure, dissociative experiences, and fundamental disturbances of self-experience (self-disorders) in early psychosis. This systematic review examines the phenomenological and neurobiological relationships among dissociation,...
Frontiers in Psychiatry
2025
Pablo Sabucedo, Óscar Andión, Robert A Neimeyer et al.
correction
1 IntroductionGrieving the death of a loved one is a nearly universal experience, and one which may be experienced multiple times over the course of a lifetime. Recent studies have shown that, for each death, approximately nine relatives are directly affected (1). The loss of a first-degree family member significantly increases the risk of mortality, disease, and suicide for the mourner (2–6)....
Frontiers in Psychiatry
2025
Amal I Khalil, Abeer Esawi, Ebtesam Abdulshakoor et al.
Nurses working in Neonatal and Pediatric Intensive Care Units (NICU/PICU) experience high levels of stress that can diminish emotional resilience and job engagement. Mindfulness-based interventions (MBIs) are known to enhance psychological well-being; however, evidence in culturally diverse settings, such as Saudi Arabia and Egypt, remains limited. This study assessed the effects of mindfulness...
Frontiers in Psychiatry
2025
Eric C Bettelheim, Jingyi Liu, Paola Dazzan et al.
Substantial evidence demonstrates that the brain is more interested in faces than in other subjects and that self-related material, particularly self-images, have higher saliency than non-self-referential material. Studies of self-portraits have revealed correlations between stylistic elements and artists' states of mind. Edvard Munch, a founder of Expressionism and most famous for "The...
Frontiers in Psychiatry
2025
Renata Fáro Guerra, Hermano Tavares
This article introduces the Somatopsyche Psychiatric Intervention (SPI), a novel body-mind approach that integrates body awareness practices, meditation, and contemporary neuroscience theories in the treatment of psychiatric conditions. SPI is structured in seven steps across eight weekly sessions, aiming to enhance emotional regulation, decision-making, and patient resilience. While the model...
Frontiers in Psychiatry
2025
Christian Mütze, Dietmar Mitzinger, Heidemarie Haller
This review systematically assessed the evidence on the effectiveness and safety of prāṇāyāma, traditional yogic breathing techniques, for patients diagnosed with mental disorders. We searched PubMed, PsycINFO, and Central until April 2024. We calculated standardized mean differences (SMDs) with 95% confidence intervals (CIs) from both intention-to-treat (ITT) and per-protocol (PP) data for...
Frontiers in Psychiatry
2025
Xiaoxin Gao, Lixiu Wu, Guolin Jin et al.
To systematically evaluate the impact of mindfulness-based interventions on insight and stigma in patients with schizophrenia. Randomized controlled trials (RCTs) and quasi-randomized controlled trials investigating the effects of mindfulness-based interventions on insight and stigma in schizophrenia patients were retrieved from databases including CNKI, Wanfang, VIP, CBM, PubMed, Cochrane...
Frontiers in Psychiatry
2025
Weirui Xiong, Lu Yu, Jinhui Chai
Problematic Social Media Use (PSMU) refers to an individual's long-term, high-intensity use of social media. Although this behavior is not pathological, it has a negative impact on the physical and mental health of individuals. In the past, intervention methods used for PSMU often controlled behavior to reduce the usage time of individual social media platforms. However, because psychological...
Frontiers in Psychiatry
2025
Ye-Hui Tu, Chao Liu, Zheng-Hao Gao et al.
This study aimed to evaluate the effectiveness of a short video app-guided mindfulness meditation intervention in improving psychological flexibility and self-compassion and reducing rumination and depressive symptoms among failed entrepreneurs. A randomized controlled trial was conducted with 100 recently failed entrepreneurs (aged 25-55), who were randomly assigned to either an intervention...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
To investigate the current status and determinants of self-transcendence in gastric cancer patients undergoing chemotherapy and to establish a foundation for clinical development of interventions. A convenience sampling method was employed to select 507 gastric cancer patients undergoing chemotherapy in the oncology department of a tertiary hospital in Wuxi City, Jiangsu Province, from October...
Frontiers in Psychiatry
2025
Aslihan Uyar, Ali Saffet Gonul
Major depressive disorder (MDD) presents a significant global health challenge, characterized by a high prevalence and significant impact on quality of life. Traditional antidepressants fall short in terms of efficacy and onset speed, up to 60% of patients. This review delves into the new and emerging pharmacologic treatments for MDD, focusing on their mechanisms of action, clinical...
Frontiers in Psychiatry
2025
Congyi Li, Zhihui Wang, Xinman Ye et al.
Clinical and preclinical studies increasingly support the antidepressant potential of several anesthetic agents, including ketamine, propofol, nitrous oxide (N2O), sevoflurane, and isoflurane. Their therapeutic effects appear to arise from the regulation of multiple interconnected systems: modulation of glutamatergic and GABAergic signaling, interaction with monoaminergic neurotransmitters...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
To investigate the current status of illness perception, hope levels, coping styles, and self-transcendence among gastric cancer patients undergoing chemotherapy, and to explore the chain-mediating role of hope levels and coping styles in illness perception and self-transcendence. This study is a cross-sectional study. A convenience sampling method was used to select 507 gastric cancer patients...
Frontiers in Psychiatry
2025
Reza Meynaghizadeh Zargar, Sevket Hepark, Poppy L A Schoenberg
Mindfulness-based cognitive therapy (MBCT) is one of the promising treatments with no known side effects for neuropsychiatric conditions such as Attention-deficit/hyperactivity disorder (ADHD). However, the mechanism of action underlying MBCT is not clearly understood. Here, we applied resting-state EEG microstate analysis and machine learning modeling to characterize brain network dynamics in...
Frontiers in Psychiatry
2025
Rebecca Paetow, Maike Franziska Dohrn, Michelle Finner-Prével et al.
Nitrous oxide (N2O) is used for anesthetic purposes but has gained popularity as a recreational substance. Despite its potentially severe adverse effects, knowledge about N2O use within psychiatric populations is limited. This study aimed to evaluate the life-time prevalence and patterns of N2O consumption among patients with psychiatric disorders. A retrospective observational cohort study was...
Frontiers in Psychiatry
2025
Rayyan Raja Zafar, Patrick Kleine, Danielle Kurtin et al.
Despite decades of neuroscience research and significant investment in addiction neuroimaging, clinical outcomes for individuals with substance use and behavioural addictions remain poor. Only 1.8% of people with substance use disorders receive effective treatment, highlighting a major disconnect between mechanistic understanding and clinical utility. This paper calls for a reorientation of...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
correction
[This corrects the article DOI: 10.3389/fpsyt.2025.1641453.].
Frontiers in Psychiatry
2025
Di Kong, Shoukang Zou, Yanqing Huang et al.
Meditation combined with antipsychotic medication can effectively improve the clinical symptoms and prognosis of patients with schizophrenia, but its underlying neural circuit mechanism is not clear. Many previous studies have shown that the symptoms of schizophrenia are related to dysfunction of the insula. We aimed to explore the neural circuitry mechanisms associated with insular dynamic...
Frontiers in Psychiatry
December 6, 2024
Jonathan Brett, Elizabeth Knock, Kathy Watson et al.
7 citations
Methamphetamine (MA) dependence leads to severe physical and psychological issues. Current treatments, including psychosocial therapies and residential rehabilitation, face limitations such as high relapse rates, cost, and accessibility issues. As a result, there is an urgent need for novel approaches to treat MA dependence that are effective, affordable, and accessible to patients. Psilocybin,...
Frontiers in Psychiatry
October 30, 2024
Jisu Park, Taejung Kim, Han-Tsung Min et al.
4 citations
Psilocybin, a psychoactive substance, has recently garnered attention for its high therapeutic potential in psychiatry. In this study, we investigated the multifaceted aspects of psilocybin, highlighting its chemical properties, mechanisms of action, and burgeoning role in psychiatric treatment. Furthermore, we examined the clinical applications and potential therapeutic benefits of psilocybin...
Frontiers in Psychiatry
October 8, 2024
Julie Faccini, Jonathan Del‐Monte
7 citations
Objective: Bad dreams and nightmares can have a strong psychological impact. However, although the scientific literature points in the direction of an established association between nightmares and psychopathology, many of the studies investigating these links have been carried out on a general population. This systematic literature review aimed to identify studies that have used a sample from...
Frontiers in Psychiatry
October 2, 2024
Iván Vial, Marcin Moskalewicz, Anastazja Szuła et al.
Debates concerning the reliability and validity of operationalized criteria and diagnostic tools have surrounded the issue of schizophrenia diagnosis and clinical decision-making related to the disorder. The notion of the praecox feeling (PF) has played a prominent role in the discussions as an example of the possibility of a rapid and potentially valid diagnosis based solely on “intuition” or...
Frontiers in Psychiatry
September 23, 2024
Zhan-Ming Shi, Yu-Ping Ning, Xin-Hu Yang et al.
21 citations
Objectives The purpose of this systematic review of randomized controlled trials (RCTs) was to evaluate the effectiveness, safety, and tolerability of psilocybin in adult patients with major depressive disorder (MDD). Methods A systematic search (up to September 14, 2023) was conducted for RCTs that examined the efficacy, safety, and tolerability of psilocybin in physically healthy adult...