Abstract Psychedelic drug use is experiencing a global resurgence, both in clinical research and community settings. This paper presents a comprehensive public health analysis of the naturalistic use of psychedelics—defined as use outside clinical or research environments. Drawing on a review of 104 peer-reviewed articles, this analysis evaluates the mental, physical, and social outcomes...
Abstract This 33-month retrospective case report explores the impact of psilocybin truffle intake on the emergence (and persistence) of mental imagery in an autistic woman with aphantasia. Aphantasia refers to the inability to generate visual mental images, which can significantly affect individuals' experiences and cognitive processes. The case study focuses on a 34-year-old autistic woman who...
Abstract Background and aims In recent years, there has been increasing attention on the potential for psychedelic-assisted therapies to be used in healthcare. However, the turbulent history of psychedelics challenges its implementation and concerns about cultural safety, equity, and diversity in research remain unresolved. In Āotearoa New Zealand, Pasifika populations face significant health...
Abstract Background & aims This conceptual paper explores the intersection of attachment theory, psychedelic research, and enculturation dynamics. We aim to understand how both attachment patterns and psychedelic use may jointly influence worldview transformations and enculturation processes. Methods We synthesize theoretical perspectives and empirical findings from multiple fields, including...
Abstract Background and aims Altered states of consciousness (ASC) represent acute and marked deviations from normal waking consciousness. Investigations into ASC are significant to problems in medicine, science, and philosophy, including the structure of conscious experience. Here, we conducted a preliminary investigation into the structure of ASC while addressing the role of psychedelics,...
Abstract Background and aims A mental health professional's background regarding psychedelics, including their attitudes, is important to the therapeutic effects of these drugs; however, no study has examined this in Asian populations. This study aims to evaluate the knowledge and attitudes of psychiatric professionals in Korea regarding the use of psychedelics in clinical practice. Methods An...
Abstract Psilocybin, a naturally occurring psychedelic compound found in certain fungi has long been used by Indigenous cultures within ritual and ceremony for healing and spiritual purposes (Spiers et al., 2024). While emerging evidence points to psychedelic agents being novel avenues for the treatment of substance use disorders, the predominantly Western medical models of psychedelic-assisted...
Abstract Background and aims Online platforms are popular for exchanging information about psychedelics, including consumption advice. The recent resurgence of public interest in psychedelics will likely intensify this. We aim to further the understanding among researchers, policy makers, medical practitioners, harm reduction practitioners, and social workers, of contemporary psychedelic...
AbstractBackgroundThere is a need to systemically diversify psychedelic clinical trials, considering the growing interest in in the therapeutic potential of psychedelics within Black, Indigenous, and Peoples of Color (BIPOC) and queer communities. Doing so contributes to a more inclusive foundation of evidence-based research and addresses ethical considerations surrounding anticipated demand...
Abstract Musico-healing practices play a key role in indigenous and mestizo traditional medicine in the Amazon. The curative songs or icaros used by the curanderos (traditional healers) of the Peruvian Upper Amazon are administered alongside the psychoactive plant decoction ayahuasca in ritual settings. This Interpretive Phenomenological Analysis examines musical experiences of 6 participants...
Abstract Music is integral to Psilocybin-assisted psychotherapy (PAP), believed to enhance therapeutic outcomes by structuring experiences and facilitating emotional expression. However, the effects of conducting PAP without music are underexplored. This study examines the experiences of two breast cancer patients undergoing psilocybin therapy under Canada's compassionate access program,...
Abstract The fictional story, Cornutopia , by British-Nigerian author Irenosen Okojie, offers a critical outsider's perspective on the enthusiasm surrounding psychedelic research, notably from outside the small world of psychedelic research. The protagonist, Amel Dyani, a young Black woman, participates in a psychedelic clinical trial but has a negative experience. This article aims to analyse...
Abstract Background and Aims This systematic review examines the association between psychedelic use and enhanced life purpose and meaning, as assessed by the Meaning in Life Questionnaire (MLQ) and the Purpose in Life Scale (PILS). Interest in psychedelics' therapeutic potential has grown, with some studies suggesting that these substances encourage meaningful psychological insights that...
Improved outcomes for substance use disorders have been described following non-clinical (“naturalistic”) psychedelic use. This exploratory study aimed to describe the naturalistic psychedelic experiences of people with substance use concerns and their reported needs and perceived utility of psychosocial support following naturalistic psychedelic use to integrate experiences and achieve...
AbstractBackground and aimsPsychedelic and MDMA-assisted psychotherapy are at the forefront of new treatment models for mental illnesses such as PTSD and depression, as well as improving well-being. Mindfulness meditation and loving-kindness meditation have also gained research traction, showing promise for enhancing emotional regulation and psychological well-being. This paper explores the...
Abstract Psychedelic treatments like MDMA can sometimes have side effects which persist despite management with Western medical approaches. In what follows, we present a case study of an individual who suffered from insomnia, anxiety, tinnitus, and more for months following MDMA therapy. Ultimately, her symptoms responded to management within the Traditional Chinese Medicine framework. We...
Abstract In this article, we provide a genealogy of the concept of integration and a discussion of the multiplicity of practices it encompasses in the field of psychedelic medicine. Reflecting on our observations of psychedelic integration practices, we make three key observations. The first is that integration services tend to focus on the individual, at the expense of considering how societal...
Abstract Background and Aims Networks of so-called underground, or illegal, psilocybin mushroom practitioners are popularly known to exist, though few systematic investigations of their practices have been conducted. We sought to uncover the experiences of a hidden community of psilocybin practitioners in order to inform scientific and policy dialogues about safe and effective practices in this...
Abstract Background The Yaqui Intercultural Medicine Clinic was established in 2020 to provide accessible, culturally-attuned treatment for substance use and mental health disorders among an Indigenous Yaqui community in Mexico. The treatment program integrates ayahuasca ceremonies and psychotherapeutic support within a community-based outpatient treatment service. This observational pilot...
Abstract The discussion surrounding the necessity of acquiring personal experience of non-ordinary states of consciousness in the course of psilocybin-assisted therapy training is crucial, as it can affect treatment safety, effectiveness and accessibility. As such, the ethical and practical issues associated with such a training standard require timely consideration in jurisdictions where this...
While psychedelic substances are extensively studied through the lens of various academic disciplines, their impact on the therapeutic practice of mental health professionals is yet to be explored. This firsthand experience is deemed crucial for effectively assisting patients in the process of integrating a psychedelic experience.The aim of this study was to explore the psychological and...
Abstract Background and aims The recent resurgence of psychedelic research has led to increased interest in extra-pharmacological factors shaping drug effects (set and setting). Habitually discussed in the context of psychedelic therapy, the relevance of set and setting to determining the outcome of non-psychedelic psychiatric interventions receives strong theoretical and empirical support in...
Abstract This article critically addresses one of the most pressing questions of the current moment of the psychedelic wave: Is mainstreaming psychedelics a good thing? Our aim is not to provide a simple “yes” or “no” as an answer but to explore the tensions, controversies, disparities, inequalities, and risks that have risen in the last decades. We discuss the limits of psychedelic science as...
Abstract As the changeful history of psychedelic research and therapy since the 1950s can be assumed to be well enough known to this journal's audience, it is only recalled briefly in this article. Rarely has it been addressed, though, that the discursive struggles through which this history has been spawned have antecedents in much older controversies in the 18th and 19th centuries. As...
Psychedelic drugs show promising therapeutic potential; however, some users experience extended difficulties following their use. This study investigated the prevalence, severity, duration, and associated coping strategies of post-psychedelic difficulties. We conducted an online survey of 159 participants, all of whom reported experiencing difficulties lasting more than one day after...