Major depressive disorder remains a leading cause of global disability, and many patients show limited response to conventional antidepressants.Increasing evidence suggests that a substantial subgroup exhibits chronic low-grade inflammation, which may constrain synaptic plasticity and contribute to persistent depressive symptoms.In this review, we propose that depression can be conceptualized...
Abstract Background and aims A mental health professional's background regarding psychedelics, including their attitudes, is important to the therapeutic effects of these drugs; however, no study has examined this in Asian populations. This study aims to evaluate the knowledge and attitudes of psychiatric professionals in Korea regarding the use of psychedelics in clinical practice. Methods An...
Previous studies suggested effectiveness of psilocybin in the field of mental health. FDA designated psilocybin as a "breakthrough therapy" for the treatment of treatment-resistant depression (TRD) in 2018. This paper provided a review of psilocybin's potential role in treatment of depression by focusing on published clinical trials. Studies showed that psilocybin, an agonist on 5-HT2A...