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Psychedelics, attachment, and enculturation dynamics: Prospects and challenges

Esenia K. Cassidy, David Dupuis, Christopher Timmermann, Pehr Granqvist

Journal of Psychedelic Studies May 30, 2025 DOI: 10.1556/2054.2025.00459 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Keywords Enculturation Dynamics music Pedagogy
Citations 4
Key points Proposes that attachment patterns and psychedelic use jointly facilitate enculturation and worldview transformations via heightened epistemic trust and serotonin 2a receptor-binding hyper-plastic states.

Abstract

Abstract Background & aims This conceptual paper explores the intersection of attachment theory, psychedelic research, and enculturation dynamics. We aim to understand how both attachment patterns and psychedelic use may jointly influence worldview transformations and enculturation processes.

Methods: We synthesize theoretical perspectives and empirical findings from multiple fields, including attachment-religion research in the psychology of religion, anthropological research on Ayahuasca use in shamanic tourism contexts, and preliminary attachment-psychedelics research.

Results: Our synthesis suggests that both attachment and psychedelics play an interacting role in facilitating enculturation and worldview transformations. This may be due to common mechanisms, including heightened epistemic trust at the psychological level and heightened serotonin 2a receptor-binding and associated hyper-plastic states at the neural level.

Conclusions: We outline future research directions and emphasize the ethical considerations that arise from these findings, particularly in the design and implementation of psychedelic-assisted therapies and cross-cultural psychedelic research.