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Front Psychiatry

ISSN 1664-0640

30 papers in the library · 129 citations · publishing 2020-2026

Papers

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How do psychedelics impact people with a history of non-affective psychosis? A qualitative study.

Front Psychiatry December 9, 2025 Haley Maria Dourron, Heith Copes, Daniel H. Grossman et al. 3 citations

Background: People with a history of psychotic disorders are excluded from contemporary trials of psychedelic-assisted therapy. Although survey studies have explored the impact of naturalistic psychedelic use on people with a history of psychotic disorders, a qualitative study has yet to examine the subjective effects of psychedelic use in this population during both the acute effects and...

Recreational MDMA use in Norway: results from an internet convenience sample.

Front Psychiatry September 26, 2025 Cato Grønnerød, Thea Rønningen, Ingrid Rike Haugsjå et al.

The purpose of the article: In recent years, a renewed interest has emerged in investigating the use of MDMA in the treatment of mental disorders. However, knowledge about the characteristics of recreational use of MDMA, its contexts and effects are limited. Methods: We recruited adult Norwegian participants aged 18 to 65 who reported having had a memorable experience after using MDMA. They...

Psychedelic therapy: bridging neuroplasticity, phenomenology, and clinical outcomes.

Front Psychiatry September 1, 2025 Ronit Kishon, Yael M. Cycowicz

The resurgence of interest in psychedelic compounds as potential treatments for psychiatric disorders represents a paradigm shift in mental health care. Psychedelics exert their effects through serotonergic modulation, particularly via 5-HT2A receptor activation, inducing profound alterations in consciousness and catalyzing neuroplasticity. While their neurobiological effects are...

Psychedelic minimalism: the case against music in psychedelic therapy settings.

Front Psychiatry August 26, 2025 Samir A Nader 3 citations

Psychedelic Minimalism: The Case Against Music in Psychedelic Therapy SettingsIn response to: Kaelen et al. (2018), “The Hidden Therapist: Evidence for a Central Role ofMusic in Psychedelic Therapy.”Introduction: Reframing the Role of SettingIn recent years, renewed attention has been given to the centrality of set and setting inpsychedelic-assisted therapy. The Reporting of Setting in...

DMT and harmala alkaloids: an exploratory study of oral Acacia based formulations in healthy volunteers.

Front Psychiatry August 15, 2025 Yvonne Bonomo, Amanda F. Norman, Lisa Collins et al. 1 citation

Introduction: Ayahuasca is a psychedelic compound of N, N, Dimethyltryptamine (DMT) and harmala alkaloids used for spiritual and medicinal applications in traditional settings. A range of potential psychotherapeutic mechanisms have been proposed for ayahuasca. These are thought to contribute to improvements in various psychiatric conditions including mood disorders and substance dependence....

Editorial: Beyond psilocybin: exploring the clinical potential of alternative and novel psychedelics.

Front Psychiatry April 23, 2025 Martin L Williams, Deborah Rudin, Yasmin Schmid et al.

However, psilocybin is but one of scores of compounds belonging to two main chemical classesphenethylamines and tryptamines -along with ergolines and an expanding array of other (mostly heterocyclic) alkaloids -that act as agonists of the serotonin 5-HT2A, 5-HT2C and 5-HT1A receptors responsible for the various phenomenological and putative therapeutic effects of classic psychedelics (8). In...

Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics.

Front Psychiatry November 6, 2024 Cristiano Chaves, Rafael G. Dos Santos, Serdar Dursun et al. 11 citations

"Iracema comes with the pot full of the green liquor. The shaman decrees the dreams to each warrior and distributes the wine of jurema, which carries the brave Tabajara to heaven." José de Alencar, in his poetic novel “Iracema” (1865)1. IntroductionThe "wine of jurema", used in ancient Brazilian shamanic rituals, is rich in N,N-dimethyltryptamine (DMT), a naturally occurring tryptamine like...

Editorial: Down the rabbit hole - the psychological and neural mechanisms of psychedelic compounds and their use in treating mental health and medical conditions.

Front Psychiatry June 10, 2024 Leehe Peled-Avron, Jacob S. Aday, Amilia Lydia Kalafateli et al. 2 citations

Editorial: Down the rabbit hole - the psychological and neural mechanisms of psychedelic compounds and their use in treating mental health and medical conditions.

Case report: Maintaining altered states of consciousness over repeated ketamine infusions may be key to facilitate long-lasting antidepressant effects: some initial lessons from a personalized-dosing single-case study.

Front Psychiatry October 25, 2023 Steffen Reissmann, Matthias Hartmann, Andreas Kist et al.

Case report: Maintaining altered states of consciousness over repeated ketamine infusions may be key to facilitate long-lasting antidepressant effects: some initial lessons from a personalized-dosing single-case study.

How psychedelic-assisted therapy works for depression: expert views and practical implications from an exploratory Delphi study.

Front Psychiatry September 28, 2023 Lauren Johansen, Paul Liknaitzky, Maja Nedeljkovic et al. 5 citations

How psychedelic-assisted therapy works for depression: expert views and practical implications from an exploratory Delphi study.

Psychotic disorders of space and time - A contribution of Erwin W. Straus.

Front Psychiatry April 11, 2023 Marcin Moskalewicz, Thomas Fuchs 8 citations

This paper presents and discusses a manuscript by one of the core founders of phenomenological psychopathology, Erwin W. Straus, concerning psychotic disorders of space and time (see attached Supplementary material). Written in June 1946, the manuscript is published for the first time as supplementary material to this paper. It is a clinical case-study of a patient with psychotic depression...

Group Mindfulness-Integrated Cognitive Behavior Therapy (MiCBT) Reduces Depression and Anxiety and Improves Flourishing in a Transdiagnostic Primary Care Sample Compared to Treatment-as-Usual: A Randomized Controlled Trial.

Front Psychiatry May 31, 2022

Group Mindfulness-Integrated Cognitive Behavior Therapy (MiCBT) Reduces Depression and Anxiety and Improves Flourishing in a Transdiagnostic Primary Care Sample Compared to Treatment-as-Usual: A Randomized Controlled Trial.