International Journal of Mental Health and Addiction
March 17, 2026
Haley Maria Dourron, Melissa Bradley, Heith Copes et al.
Abstract Despite a long-standing interest in the potential similarities between psychedelic and psychotic experiences, no recent research has systematically explored the subjective overlap between these states in individuals who have experienced both. To provide rich accounts of potential overlaps and distinctions, we conducted semi-structured interviews with 19 individuals diagnosed with...
Front Psychiatry
December 9, 2025
Haley Maria Dourron, Heith Copes, Daniel H. Grossman et al.
3 citations
Background: People with a history of psychotic disorders are excluded from contemporary trials of psychedelic-assisted therapy. Although survey studies have explored the impact of naturalistic psychedelic use on people with a history of psychotic disorders, a qualitative study has yet to examine the subjective effects of psychedelic use in this population during both the acute effects and...
Psychedelic medicine (New Rochelle, N.Y.)
June 1, 2025
Haley Maria Dourron, Melissa Bradley, Otto Simonsson et al.
7 citations
Prior research examining the associations between psychedelic use and general psychotic symptoms has yielded mixed findings. However, no studies have investigated the relationships between psychedelic use and specific psychotic symptoms, and whether these relationships might differ among those with liability to psychosis, namely those with a history of psychotic or bipolar disorders. Using...
November 22, 2024
Haley Maria Dourron, Melissa Bradley, Peter S. Hendricks
1 citation
preprint
Myran et al. report that emergency room (ER) visits involving hallucinogens are associated with a 21.32 greater risk of being diagnosed with a schizophrenia spectrum disorder (SSD).1 Although implications for the development of psychedelics as medicines are discussed, we highlight some important distinctions.
Journal of Affective Disorders
January 26, 2024
Ludwig Honk, Cecilia U.D. Stenfors, Simon B. Goldberg et al.
41 citations
It has long been speculated that psychedelic use could provoke the onset of psychosis, but there is little evidence to support this conjecture. Using a longitudinal research design with samples representative of the US and UK adult populations with regard to sex, age, and ethnicity (n = 9732), we investigated associations between psychedelic use and change in the number of psychotic symptoms...
Psychedelic Med (New Rochelle)
December 13, 2023
Nicholas A. Carlisle, Haley Maria Dourron, Sarah Maccarthy et al.
12 citations
Exploring the Unique Therapeutic Potential of Psychedelics to Reduce Chronic Shame Among Sexual and Gender Minority Adults.
Psychopharmacology
December 11, 2023
Haley Maria Dourron, Charles D. Nichols, Otto Simonsson et al.
23 citations
5-MeO-DMT is a tryptamine being developed as a potential antidepressant that may display a distinct therapeutic mechanism due to its unique pharmacology and subjective effects compared to typical psychedelics. In this article, we parallel the relatively distinct phenomenology and behavioral effects of the acute and post-acute effects of 5-MeO-DMT to those induced by epileptiform activity,...
Journal of Psychoactive Drugs
August 31, 2023
Haley Maria Dourron, Heith Copes, Agasthya Vedre-Kyanam et al.
6 citations
Deliriants are the least studied class of hallucinogens and display noticeable subjective effects, including dysphoria, hallucinations, and substantial alterations in thought. High doses of diphenhydramine (DPH), an over-the-counter antihistamine medication, can produce deliriant effects due to secondary anticholinergic activity. We sought to characterize the subjective experiences produced by...
Neuropharmacology
May 13, 2022
Cynthia E. Ortiz, Haley Maria Dourron, Noah W Sweat et al.
26 citations
Psilocybin-facilitated psychotherapy shows potential transdiagnostic efficacy for a range of mental health conditions. Though vulnerable populations bear disproportionate mental health burden, they have been largely neglected in the clinical psilocybin literature. However, if the field is to best respond to the diverse needs of individuals from vulnerable populations, care must be taken to...