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Liam T. Kane

3 papers in the library · 23 citations · publishing 2021

Papers

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A whole genome atlas of 81 Psilocybe genomes as a resource for psilocybin production.

F1000Research September 23, 2021 Kevin Mckernan, Liam T. Kane, Yvonne Helbert et al. 10 citations

The Psilocybe genus is well known for the synthesis of valuable psychoactive compounds such as Psilocybin, Psilocin, Baeocystin and Aeruginascin. The ubiquity of Psilocybin synthesis in Psilocybe has been attributed to a horizontal gene transfer mechanism of a ~20Kb gene cassette. A recently published highly contiguous reference genome derived from long read single molecule sequencing has...

A draft reference assembly of the Psilocybe cubensis genome

F1000Research June 15, 2021 Kevin Mckernan, Liam T. Kane, Seth Crawford et al. 10 citations

We describe the use of high-fidelity single molecule sequencing to assemble the genome of the psychoactive Psilocybe cubensis mushroom. The genome is 46.6Mb, 46% GC, and in 32 contigs with an N50 of 3.3Mb. The BUSCO completeness scores are 97.6% with 1.2% duplicates. The Psilocybin synthesis cluster exists in a single 3.2Mb contig. The dataset is available from NCBI BioProject with accessions...

DOI: 10.12688/f1000research.51613.2 (opens in new tab) Contig Genome Computational biology Genetics +1

A draft sequence reference of the Psilocybe cubensis genome

F1000Research April 9, 2021 Kevin Mckernan, Liam T. Kane, Seth Crawford et al. 3 citations

We describe the use of high-fidelity single molecule sequencing to assemble the genome of the psychoactive Psilocybe cubensis mushroom. The genome is 46.6Mb, 46% GC, and in 32 contigs with an N50 of 3.3Mb. The BUSCO completeness scores are 97.6% with 1.2% duplicates. The Psilocybin synthesis cluster exists in a single 3.2Mb contig. The dataset is available from NCBI BioProject with accessions...

DOI: 10.12688/f1000research.51613.1 (opens in new tab) Contig Computational biology Whole genome sequencing Genetics +1