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Natalia E. Morone

20 papers in the library · 544 citations · publishing 2007-2026

Papers

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Mindfulness-Based Group Medical Visits for Persons With Chronic Low Back Pain: A Randomized Clinical Trial.

JAMA Internal Medicine June 29, 2026 Natalia E. Morone, Keturah R Faurot, Janice M Weinberg et al.

Importance: Back pain is among the most common, disabling, and costly conditions managed in primary care in the US, but current treatment options often do not provide adequate relief. Mindfulness-based interventions have demonstrated effectiveness in individuals with chronic low back pain (CLBP); however, mindfulness remains underused in part because it is not integrated into most outpatient...

DOI: 10.1001/jamainternmed.2026.2186 (opens in new tab) Mindfulness Humans Low back pain Pain measurement +8

Psychosocial Moderators of Response to a Mindfulness-Based Stress Reduction Trial for Chronic Low Back Pain: Considerations for Intervention Science and Development.

Pain Medicine March 25, 2026 Lorena S Nunes, Angela C. Incollingo Rodriguez, Benjamin C. Nephew et al.

Dear Editor, Chronic low back pain (cLBP) is increasingly prevalent across populations and ages.1 Low back pain is currently the leading cause of disability worldwide.2 Beyond widespread effects on individual functioning and well-being, the financial,3 psychological,4 and social5 implications of cLBP are vast. Mindfulness-based stress reduction (MBSR) is effective in decreasing various pain...

A protocol for using rapid qualitative techniques to incorporate multi-level stakeholder feedback in a pragmatic clinical trial of mindfulness for chronic low back pain.

PLoS One January 2, 2026 Isabel Roth, Elondra Harr, Christine Lathren et al.

Introduction: Engaging community members and context experts is increasingly recognized as key to developing research that is responsive to community needs. Here, we describe a protocol for incorporating stakeholder feedback using rapid qualitative techniques into OPTIMUM (Optimizing Pain Treatment In Medical settings Using Mindfulness), a pragmatic clinical trial comparing a...

Mindfulness Group Visits for Chronic Low Back Pain in Primary Care: The OPTIMUM Pragmatic Clinical Trial

Innovation in Aging December 1, 2025 Natalia E. Morone, Tra Nguyen, Keturah R Faurot et al.

Abstract Mindfulness is recommended as a first-line non-pharmacologic treatment for chronic low back pain (cLBP). However, accessibility is challenging. The OPTIMUM trial (Optimizing Pain Treatment In Medical settings Using Mindfulness) compared a telehealth-delivered group mindfulness program for primary care patients with cLBP to usual care. Here we describe the methods of this investigation,...

The Hidden Complexity of Virtual Mindfulness-Based Group Medical Visits: Comfort, Challenge, and the Influence of Social Determinants of Health.

Global Advances in Integrative Medicine and Health 2025 Jessica L Barnhill, Gabriela Castro, Christine Lathren et al.

Chronic low back pain is globally prevalent and associated with significant impairment in quality of life. Furthermore, people from historically marginalized communities are less likely to receive treatment, contributing to health inequities. Group mindfulness-based interventions improve pain and function, and virtual delivery has been demonstrated to be feasible. Little is known about how...

DOI: 10.1177/27536130251326938 (opens in new tab) Full text (opens in new tab) Mindfulness-baseed stress reduction Pain Telemedicine Virtual +1

A Brief Measure of Fidelity for Mindfulness Programs: Development and Evaluation of the Concise Fidelity for Mindfulness-Based Interventions Tool.

Global Advances in Integrative Medicine and Health 2023 Carol M. Greco, Graham A Dore, Janice M Weinberg et al.

Mindfulness research and clinical programs are widespread, and it is important that mindfulness-based interventions are delivered with fidelity, or as intended, across settings. The MBI:TAC is a comprehensive system for assessing teacher competence, yet it can be complex to implement. A standardized, simple fidelity/engagement tool to address treatment delivery is needed. We describe the...

DOI: 10.1177/27536130231174234 (opens in new tab) Full text (opens in new tab) Fidelity assessment Medical group visits Mindfulness meditation Online intervention +1

What Are Adverse Events in Mindfulness Meditation?

Global Advances in Health and Medicine 2022 Dhanesh D Binda, Carol M. Greco, Natalia E. Morone

Mindfulness meditation has become a successful treatment of both physical and psychosocial ailments over the past decade. Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT) are now implemented in various clinical and hospital settings for the treatment of stress, depression, substance abuse, and chronic pain. However, given mindfulness meditation’s...

Characterizing Interprofessional Collaboration and Referral to Mindfulness-Based Stress Reduction Programs.

Global Advances in Health and Medicine 2022 Dhanesh D Binda, Janice M Weinberg, Tra Nguyen et al.

In 2017, the American College of Physicians (ACP) designated Mindfulness-Based Stress Reduction (MBSR), an eight-week group program, as first-line non-pharmacological treatment for chronic low back pain. However, interprofessional collaboration between mindfulness instructors and Primary Care Providers (PCP) remains largely unknown. We developed a survey to assess communication between...

The design and methods of the OPTIMUM study: A multisite pragmatic randomized clinical trial of a telehealth group mindfulness program for persons with chronic low back pain.

Contemporary Clinical Trials October 2021 Carol M. Greco, Susan A Gaylord, Kim Faurot et al.

Mindfulness-based stress reduction (MBSR) is an evidence-based non-pharmacological approach for chronic low back pain (cLBP), yet it is not readily available or reimbursable within primary care clinics. Primary care providers (PCPs) who wish to avoid prescribing opioids and other medications typically have few options for their cLBP patients. We present the protocol of a pragmatic clinical...

DOI: 10.1016/j.cct.2021.106545 (opens in new tab) Full text (opens in new tab) Medical group visits Mindfulness meditation Online intervention Quadruple aim

Integrated Meditation and Exercise Therapy: A Randomized Controlled Pilot of a Combined Nonpharmacological Intervention Focused on Reducing Disability and Pain in Patients with Chronic Low Back Pain.

Pain Medicine February 23, 2021 Anna M. Polaski, A. Phelps, Thomas J. Smith et al.

OBJECTIVE This pilot trial examined the effects of a combined intervention of mindfulness meditation followed by aerobic walking exercise compared with a control condition in chronic low back pain patients. We hypothesized that meditation before exercise would reduce disability, pain, and anxiety by increasing mindfulness prior to physical activity compared with an audiobook control group....

Not Just Mind Over Matter: Reviewing With Patients How Mindfulness Relieves Chronic Low Back Pain.

Journal of Evidence-Based Integrative Medicine 2019 Natalia E. Morone

The current opioid crisis has spurred the need for nonpharmacological therapies for chronic low back pain. In a study published in JAMA Internal Medicine, we reported that in 282 older adults with chronic low back pain, an 8-week mind-body group program modeled on Mindfulness-Based Stress Reduction (MBSR) decreased long-term pain and increased short-term function. Barriers to uptake remain such...

Mindfulness for Chronic Low Back Pain: A Qualitative Analysis

Pain Medicine November 1, 2018 José G Luiggi-Hernandez, Jean Woo, Megan Hamm et al.

Abstract: Objective: Mindfulness is a nonpharmacologic mind-body therapy that has been shown to be effective in older adults with chronic low back pain (cLBP). There are few first-person accounts in the literature that describe the older adult experience and perspective while learning mindfulness and meditation to treat pain. The objective of this study was to investigate dominant themes...

Characteristics of Adults Who Used Mindfulness Meditation: United States, 2012.

The Journal of Alternative and Complementary Medicine July 2017 Natalia E. Morone, Charity G Moore, Carol M. Greco

To describe estimates of the number and characteristics of persons who had used mindfulness meditation in the U.S. Data from 108,131 adults from the 2012 National Health Interview Survey were weighted to produce national estimates representative of the U.S. Persons who used mindfulness meditation were identified by their response to the question "During the past 12 months, did you use...

A Mind-Body Program for Older Adults With Chronic Low Back Pain: A Randomized Clinical Trial.

JAMA Internal Medicine March 1, 2016 Natalia E. Morone, Carol M. Greco, Charity G Moore et al.

Importance: Treatment of chronic low back pain (LBP) in older adults is limited by the adverse effects of analgesics. Effective nonpharmacologic treatment options are needed. Objective: To determine the effectiveness of a mind-body program at increasing function and reducing pain in older adults with chronic LBP. Design, setting, and participants: This single-blind, randomized clinical trial...

The design and methods of the aging successfully with pain study.

Contemporary Clinical Trials November 15, 2011 Natalia E. Morone, Carol M. Greco, Bruce L Rollman et al.

Chronic low back pain (CLBP) is widespread among older adults (≥ 65 years) and is often treated inadequately. With a rapidly growing aging population, CLBP will increase and so will the demand for treatment. We believe that mind-body therapies can help to meet this demand. We present the methodology of a randomized, controlled clinical trial of 300 individuals with CLBP aged 65 years or older....

A mind-body program for older adults with chronic low back pain: results of a pilot study.

Pain Medicine November 2009 Natalia E. Morone, Bruce L Rollman, Charity G Moore et al.

Determine the impact of an 8-week mindfulness meditation program on disability, psychological function, and pain severity in community-dwelling older adults with chronic low back pain, and to test the education control program for feasibility. Randomized controlled trial. Participants. Forty community-dwelling older adults with moderate low back pain or greater for at least the previous 3...

"I felt like a new person." the effects of mindfulness meditation on older adults with chronic pain: qualitative narrative analysis of diary entries.

Journal of Pain September 2008 Natalia E. Morone, Cheryl S Lynch, Carol M. Greco et al.

To identify the effects of mindfulness meditation on older adults with chronic low back pain (CLBP), we conducted a qualitative study based on grounded theory and used content analysis of diary entries from older adults who had participated in a clinical trial of an 8-week mindfulness meditation program. Participants were 27 adults > or = 65 years of age with CLBP of at least moderate severity...

Mindfulness meditation for the treatment of chronic low back pain in older adults: A randomized controlled pilot study ☆

Pain June 4, 2007 Natalia E. Morone, Carol M. Greco, Debra K. Weiner 544 citations

The objectives of this pilot study were to assess the feasibility of recruitment and adherence to an eight-session mindfulness meditation program for community-dwelling older adults with chronic low back pain (CLBP) and to develop initial estimates of treatment effects. It was designed as a randomized, controlled clinical trial. Participants were 37 community-dwelling older adults aged 65 years...

DOI: 10.1016/j.pain.2007.04.038 (opens in new tab) Mindfulness meditation Randomized controlled trial Chronic pain Physical therapy +1

Integrated meditation and exercise therapy: A randomized controlled trial of a combined non-pharmacological intervention reduces disability and pain in patients with chronic low back pain

Anna M. Polaski, Amy L. Phelps, Thomas J. Smith et al. preprint

ABSTRACT Integrative and complementary non-pharmacological treatments have proven efficacious in treating both the physiological and psychological symptoms of chronic pain conditions but the potential of many combined therapies is unknown. This study examined the effects of a combined intervention of mindfulness meditation followed by aerobic walking exercise in chronic low back pain (cLBP)...

Machine learning based phenotyping of the response to mindfulness for chronic low back pain

Akshit Soota, Angela C. Incollingo Rodriguez, Benjamin C. Nephew et al. preprint

ABSTRACT Millions of people each year suffer from chronic low back pain (cLBP), which adversely affects their physical and mental health. While non-pharmacological interventions such as mindfulness are known to be effective in treating cLBP, not all patients experience the same benefit. Determining who these treatments might work best for is difficult, as there are no reliable predictors of the...