The journals of gerontology. Series B, Psychological sciences and social sciences
November 5, 2025
Janine M. Dutcher, Kirk W Brown, Emily K. Lindsay et al.
Loneliness is one of the most robust risk factors for morbidity and accelerated mortality among older adults, and effective interventions are needed. However, interventions to reduce loneliness have shown limited success, especially in this population. Indeed, research suggests that simply increasing social contact might not combat loneliness; instead, addressing the cognitive and emotional...
Biological psychiatry. Cognitive neuroscience and neuroimaging
April 1, 2025
Saampras Ganesan, Fernando A Barrios, Ishaan Batta et al.
6 citations
Meditation is a family of ancient and contemporary contemplative mind-body practices that can modulate psychological processes, awareness, and mental states. Over the last 40 years, clinical science has manualized meditation practices and designed various meditation interventions that have shown therapeutic efficacy for disorders including depression, pain, addiction, and anxiety. Over the past...
Journal of Psychopathology and Clinical Science
2023
Ceci Westbrook, Janine M. Dutcher, Susan Kusmierski et al.
7 citations
Uncontrollable worry is a hallmark of generalized anxiety disorder and a transdiagnostic feature of psychopathology. Mindfulness-based strategies show promise for treating worry, but it is unknown which specific strategies are most beneficial, and how these skills might operate on a neurobiological level. We recruited 40 participants with clinically significant worry to undergo functional...
May 3, 2022
Ceci Westbrook, Janine M. Dutcher, Susan Kusmierski et al.
preprint
Uncontrollable worry is a hallmark of generalized anxiety disorder and a transdiagnostic feature of psychopathology. Mindfulness-based strategies show promise for treating worry, but neural mechanisms of mindful disengagement remain incompletely characterized. We recruited 40 participants with clinically significant worry to undergo fMRI while engaging in real-time, idiographic worry and...
Brain, behavior, and immunity
May 1, 2022
Emily K. Lindsay, J. D. Creswell, Harrison J. Stern et al.
Loneliness is a potent psychosocial stressor that predicts poor health and mortality among older adults, possibly in part by accelerating age-related declines in immunocompetence. Mindfulness interventions have shown promise for reducing loneliness and improving markers of physical health. In a sample of lonely older adults, this two-arm parallel trial tested whether mindfulness training...
Brain Behavior and Immunity
April 12, 2022
Janine M. Dutcher, Steve W Cole, Adrian Williams et al.
29 citations
Mindfulness meditation training has been shown to be an effective stress reduction strategy, but less is known about its immunoregulatory impact. In a randomized controlled trial of stressed customer service workers, the present study tested whether a 30-day smartphone-based mindfulness meditation training program (compared to a problem-solving control program) would affect pro-inflammatory...
Psychosomatic Medicine
March 3, 2021
Emily K. Lindsay, J. David Creswell, Harrison J. Stern et al.
18 citations
OBJECTIVE: Mindfulness interventions have been effective for improving a range of health outcomes; however, pathways underlying these effects remain unclear. Inflammatory processes may play a role, possibly through increased resistance of immune cells to the anti-inflammatory effects of glucocorticoids (i.e., glucocorticoid resistance, or GCR). Here, we conducted an initial examination of...