Background Breathwork that increases ventilatory rate or depth represents an accessible non-pharmacological modality for potentially inducing altered states of consciousness (ASCs). Despite gaining traction as a potential therapeutic tool, empirical controlled research on breathwork and ASCs remains limited. Methods We examined the effects of a single session of high ventilation breathwork,...
Abstract Breathwork which increases ventilatory rate or depth represents an accessible nonpharmacological modality for potentially inducing altered states of consciousness (ASCs). Despite gaining traction as a therapeutic tool, empirical research remains limited, hence we conducted the first randomised-controlled trial (NCT06916312) on breathwork and ASCs. We examined the effects of a single...
PLoS OneAugust 27, 2025Amy Kartar, Toru Horinouchi, Balázs Örzsik et al.1 citation
The popularity of breathwork as a therapeutic tool for psychological distress is rapidly expanding. Breathwork practices that increase ventilatory rate or depth, facilitated by music, can evoke subjective experiential states analogous to altered states of consciousness (ASCs) evoked by psychedelic substances. These states include components such as euphoria, bliss, and perceptual differences....
High ventilation breathwork with retention (HVBR) has been growing in popularity over the past decade and might be beneficial for mental and physical health. However, little research has explored the potential therapeutic effects of brief, remotely delivered HVBR and the tolerability profile of this technique. Accordingly, we investigated the effects of a fully-automated HVBR protocol, along...
Abstract High ventilation breathwork with retention (HVBR) might be beneficial for mental/physical health and has been growing in popularity over the past decade. However, little research has investigated the potential therapeutic effects of brief, remotely delivered HVBR and the tolerability profile of this technique. This study (NCT06064474) was the largest blinded randomised-controlled trial...
High Ventilation Breathwork (HVB) refers to practices employing specific volitional manipulation of breathing, with a long history of use to relieve various forms of psychological distress. This paper seeks to offer a consolidative insight into potential clinical application of HVB as a treatment of psychiatric disorders. We thus review the characteristic phenomenological and neurophysiological...
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found in magic mushrooms, and a task-free functional MRI (fMRI) protocol designed to capture the transition from normal waking consciousness to the...