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Ninette Simonian

11 papers in the library · 34 citations · publishing 2023-2026

Papers

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Facilitating Meditation with Focused Ultrasound Neuromodulation: A Sham-Controlled Crossover Study in Long-Term and Novice Meditators

October 21, 2026 Joshua Cain, Micah Alan Johnson, Amirvala Tavakoli et al. preprint

Sustained contemplative practice confers well-documented psychological and physiological benefits, yet the experiential deepening that motivates practitioners can require many hours of practice, and mastery is not assured. Methods that accelerate training would broaden access to these benefits and could also test mechanism: the posterior cingulate cortex (PCC), caudate, and anterior insula are...

Neural correlates and behavioral outcomes of aesthetic chills and their prosthetic augmentation

September 13, 2026 Félix Schoeller, Leonardo Christov-Moore, Ninette Simonian et al. preprint

Aesthetic chills, psychogenic shivers elicited by emotionally charged stimuli such as music, offer a neurophysiological marker bridging subjective experience and measurable physiology. Although neuroimaging has localized chills to reward and interoceptive circuits and behavioral work has linked them to prosocial outcomes, their electrophysiological signature and its relationship to...

Alpha and theta audiovisual interventions in a reflective chamber demonstrate acute effects on stress and burnout.

NPJ Digital Medicine March 28, 2026 Aidan Cone, Sam Zuzick, Tiffany Durinski et al.

Escalating stress prevalence, particularly among essential service personnel whose cognitive compromise threatens public welfare, necessitates rapid, accessible non-pharmacological interventions. Individuals who struggle with endogenous cultivation of beneficial neuropsychological states may benefit from passive exogenous stimulation. This uncontrolled exploratory investigation (n = 74)...

Contrasting cognitive, behavioral, and physiological responses to breathwork vs. naturalistic stimuli in reflective chamber and VR headset environments.

PLOS mental health March 12, 2025 Ninette Simonian, Micah Alan Johnson, Caitlin Lynch et al.

The MindGym, a novel immersive technology utilizing a reflective chamber environment, was developed to create standardized experiential content, including anxiolytic experiences. This study examined whether therapeutic experiences originally created in the MindGym could maintain their efficacy when delivered via 360-degree recordings through virtual reality (VR) headsets. A randomized...

Lightening the mind with audiovisual stimulation as an accessible alternative to breath-focused meditation for mood and cognitive enhancement.

Scientific Reports October 26, 2024 Micah Alan Johnson, Ninette Simonian, Nicco Reggente 6 citations

In this randomized, controlled, and double-blind experiment with a relatively large sample (n = 262), a novel technique of audiovisual stimulation (AVS) was demonstrated to substantially improve self-reported mood states by reducing several negative affects, including anxiety and depression, and enhancing performance on mood-sensitive cognitive tasks. Most of the AVS effects were highly similar...

Decoding Depth of Meditation: Electroencephalography Insights From Expert Vipassana Practitioners

Biological Psychiatry Global Open Science October 17, 2024 Nicco Reggente, Christian Kothe, Tracy Brandmeyer et al. 15 citations

Meditation practices have demonstrated numerous psychological and physiological benefits, but capturing the neural correlates of varying meditative depths remains challenging. In this study, we aimed to decode self-reported time-varying meditative depth in expert practitioners using electroencephalography (EEG). Expert Vipassana meditators ( n = 34) participated in 2 separate sessions....

DOI: 10.1016/j.bpsgos.2024.100402 (opens in new tab) Meditation Electroencephalography Decoding methods Speech recognition +3

Contrasting Cognitive, Behavioral, and Physiological Responses to Breathwork vs. Naturalistic Stimuli in Reflective Chamber and VR Headset Environments: Randomized Control Study

bioRxiv September 19, 2024 Ninette Simonian, Micah Alan Johnson, Caitlin Lynch et al. preprint

The MindGym, a novel immersive technology utilizing a reflective chamber environment, was developed to create standardized experiential content, including anxiolytic experiences. This study examined whether therapeutic experiences originally created in the MindGym could maintain their efficacy when delivered via 360-degree recordings through virtual reality (VR) headsets. A randomized...

Lightening the Mind: Comparing Audiovisual Stimulation and Meditation for Mood and Cognition Enhancement

Research Square March 14, 2024 Micah Johnson, Ninette Simonian, Nicco Reggente preprint

Abstract In this randomized, controlled, and double-blind experiment with a relatively large sample (n = 262), a novel technique of audiovisual stimulation (AVS) was demonstrated to substantially improve self-reported mood states by reducing several negative affects, including anxiety and depression, and enhancing performance on mood-sensitive cognitive tasks. Most of the AVS effects were...

Facilitating Meditation with Focused Ultrasound Neuromodulation: A First Investigation in Experienced Practitioners

January 31, 2024 Joshua Cain, Tracy Brandmeyer, Ninette Simonian et al. 9 citations preprint

This study aims to assess the validity of focused ultrasound (FUS) stimulation as a method for facilitating meditative development, which may have application for novice or intermediate meditators seeking to improve their practice. A growing body of work suggests profound benefits to health and wellbeing following consistent meditation practice; however, successfully maintaining such a practice...

DOI: 10.31234/osf.io/3bzg6 (opens in new tab) Meditation Neuromodulation Focused ultrasound Psychotherapist +3

Decoding Depth of Meditation: EEG Insights from Expert Vipassana Practitioners

January 31, 2024 Nicco Reggente, Christian Kothe, Tracy Brandmeyer et al. 4 citations preprint

Meditation practices have demonstrated numerous psychological and physiological benefits, yet capturing the neural correlates of varying meditative depths remains challenging. This study aimed to decode self-reported time-varying meditative depth in expert practitioners using EEG. Expert Vipassana meditators (n=34) participated in two separate sessions. Participants reported their meditative...

DOI: 10.31234/osf.io/7c3er (opens in new tab) Meditation Electroencephalography Decoding methods Cognitive psychology +3

Neural entrainment induced by periodic audiovisual stimulation: A large-sample EEG study

bioRxiv Preprint Server October 25, 2023 Joel Frohlich, Ninette Simonian, Grant Hanada et al. preprint

Stroboscopic or “flicker” stimulation is a form of periodic visual stimulation that induces geometric hallucinations through closed eyelids. While the visual effects of this form of sensory stimulation have received considerable attention, few studies have investigated the neural entrainment effects of periodic visual stimulation. Here, we introduce two variants of the classic flicker paradigm...