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To be aware, or to accept, that is the question: Differential roles of awareness of automaticity and pain acceptance in opioid misuse.

Anna Parisi, Aleksandra Zgierska, Cindy A. Burzinski, Robert P. Lennon, Robert N. Jamison, Yoshio Nakamura, Bruce P. Barrett, Robert R Edwards, Eric L Garland

Drug and Alcohol Dependence June 1, 2023 DOI: 10.1016/j.drugalcdep.2023.109890 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cross-sectional study Peer reviewed
Sample size 770
Population Adults with chronic low back pain receiving long-term opioid therapy
Keywords Acceptance Automaticity Chronic pain Dispositional mindfulness Opioids Trait mindfulness
Key findings Chronic pain acceptance and awareness of automatic thoughts and behaviors together accounted for a significant portion of variance in opioid misuse risk. Awareness of automaticity was negatively associated with misuse risk, while pain acceptance showed no association. The authors suggest awareness of automaticity may buffer against opioid misuse in this population.

Abstract

Individuals with chronic low back pain (CLBP) are commonly prescribed long-term opioid therapy (LTOT) for analgesia, placing this population at increased risk for opioid misuse and opioid use disorder. Acceptance of aversive experiences (e.g., chronic pain) and awareness of automatic thoughts and behaviors (i.e., automaticity) are two facets of dispositional mindfulness that may serve as protective mechanisms against opioid misuse risk. Therefore, the aim of the current study was to examine the differential contributions of these constructs to opioid misuse risk among adults with CLBP receiving LTOT. Data were obtained from a sample of 770 adults with opioid-treated CLBP. Bivariate correlations and hierarchical linear regression analyses were used to determine whether chronic pain acceptance and awareness of automatic thoughts and behaviors explained a statistically significant portion of variance in opioid misuse risk after accounting for the effects of other relevant confounders. Hierarchical regression results revealed that chronic pain acceptance and awareness of automatic thoughts and behaviors contributed a significant portion in the variance of opioid misuse risk. Awareness of automatic thoughts and behaviors was negatively associated with opioid misuse risk, such that individuals with lower levels of awareness of automaticity were at higher risk of opioid misuse. By contrast, pain acceptance was not associated with opioid misuse. Findings suggest that awareness of automaticity may buffer against opioid misuse risk. Interventions designed to strengthen awareness of automaticity (e.g., mindfulness-based interventions) might be especially efficacious among this population.

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