Sleep-an essential pillar of health-has historically been considered not only a biological phenomenon but also based on experiences interpreted through spiritual, moral, existential, and cultural frameworks worldwide [1-5].Across societies, dreams, nightmares, sleep paralysis, and nocturnal visions have frequently been attributed to soul journeys, spirits, precognitions, moral conflict,...
Evidence suggests that transcendent end-of-life experiences (ELEs) are common and impact the dying; however, there is a shortage of longitudinal studies. To evaluate the prevalence and characteristics of ELEs in terminally ill patients. This multicenter longitudinal mixed‑methods study collected demographic, clinical, and ELE‑related data-including prevalence, content, and comfort/distress...
Humanity is undergoing a profound demographic transition, with older adults representing a growing share of society. This late stage of life not only prompts profound reflections on the meaning of life and the inevitability of death, but is also associated with a higher occurrence of certain non-ordinary experiences - such as end-of-life experiences (ELEs), after-death communications (ADCs),...
Palliative & Supportive CareDecember 26, 2025Taís Oliveira Silva, Bruno Angeli-Faez, Lorena Cândida Ferreira Paixão et al.
End-of-life dreams and visions (ELDVs) and delirium frequently occur near death but differ in core features. Clinical differentiation becomes challenging when they co-occur. This case report illustrates the interplay between ELDVs and delirium, examines the limits of current diagnostic criteria in mixed cases, and outlines a nuanced approach to distinction. We report the case of an elderly...
Despite extensive discussions, a consensus is lacking on whether out-of-body experiences (OBEs) and lucid dreams (LDs) should be considered as distinct categories of experience, and if so, what differentiates them. To address this issue, we first discussed the implications of OBEs and LDs as the same type of phenomenon. We then compiled a comprehensive list of experiential features associated...
Spiritual and religious experiences (SREs) are common subjective phenomena related to the awareness of transcendence, which transforms one's perception of life, death and suffering. Despite the high prevalence of SREs worldwide, not enough studies have been conducted beyond Europe and North America. To fill this gap, this study investigates the prevalence of SREs in Brazil and their association...
The French educator Allan Kardec (1804-1869) was one of the first researchers to propose the scientific investigation of psychical experiences and was an influential scholar in Europe during the second half of the 19th Century. However, his life and the outcome of his research in this field are currently little known and often misconstrued. This paper briefly presents Kardec's biography and his...
The mind-brain problem, which explores the relationship between the mind and brain and the nature of consciousness, remains a scientific challenge. It is not a purely theoretical issue; it profoundly shapes our understanding of human nature. This paper reviews evidence on mind-brain problem views impacting ethical, clinical, and academic domains. Evidence shows that dualism is prevalent, even...
The nature of consciousness remains unclear, and academic discussions usually ignore the scientific evidence about anomalous and spiritual experiences suggestive of the mind beyond the brain, mainly because of the lack of a scientific framework that makes sense of these experiences. This manuscript proposes the 'Pragmatic interactionist' scientific framework for the mind-brain relationship...
Mediums are individuals who claim to communicate with deceased persons or non-material beings. Rigorous studies have reported that mediums can provide accurate anomalous information (i.e. information not obtained through the conventional senses or inferential reasoning). This paper reviews the evidence about these claims and explores the main conventional explanatory hypotheses: fraud, sitter's...
There has been a call for neuroscientific studies of spiritual experiences due to their global prevalence, significant impact, and importance for understanding the mind-brain problem. Mediumship is a spiritual experience where individuals claim to communicate with or be influenced by deceased persons or non-material entities. We assessed whether mediums carry specific genetic alterations. We...
Wenn man den gesamten Körper an Überlebensevidenz mit einem rationalen, rigorosen und offenen Geist analysiert, fällt es schwer, dem Schluss zu widerstehen, dass das Überleben des menschlichen Bewusstseins nach dem permanenten körperlichen Tod eine Tatsache der Natur ist. Tatsächlich ist dies konsequent die Schlussfolgerung, die von der überwiegenden Mehrheit der Menschheit gezogen wurde,...
Early in the founding of psychology of religion, a debated issue was the methodological exclusion of the transcendent (MET). While cautiously endorsed by Theodore Flournoy, others, notable William James and Frederic Myers, refused to be limited by this principle. This paper discusses (a) what is MET as proposed by Flournoy and the reasons he provided to adopt it, (b) problems with MET,...
Explore2022Elizabeth Schmitt Freire, Alexandre Caroli Rocha, Victor Scio Tasca et al.
Mediumship is understood as a kind of spiritual experience in which a person (i.e., a medium) claims to be in communication with, or under the control of, spiritual beings. In the last decades there has been a resurgence of studies on psychological, psychiatric and neuroscientific aspects of mediumship, as well as studies assessing the claim that mediums can obtain anomalous information from...
Abstract: Psychotic experiences are common experiences shared by a considerable part of the world's population. Moreover, most of the individuals who report these experiences also report those called spiritual and dissociative phenomena. In specific culture and religious backgrounds, these experiences are frequently seen as a part of normal human experiences, usually called mediumship. We...
Objective: The mind-brain problem (MBP) has marked implications for psychiatry, but has been poorly discussed in the psychiatric literature. This paper evaluates the presentation of the MBP in the three leading general psychiatry journals during the last 20 years. Methods: Systematic review of articles on the MBP published in the three general psychiatry journals with the highest impact factor...
It is unclear why some individuals reporting psychotic experiences have balanced lives while others go on to develop mental health problems. The objective of this study was to test if the personality traits of harm avoidance, self-directedness, and self-transcendence can be used as criteria to differentiate healthy from unhealthy schizotypal individuals. We interviewed 115 participants who...
This study aims to conduct a search of publications investigating experiences commonly associated with the possibility of the existence of a consciousness independent of the brain held on the main scientific databases (Pubmed, Web of Knowledge, PsycINFO, Science Direct, and Scopus). Of the 9065 articles retrieved, 1954 were included (598 near-death experiences, 223 out-of-body experiences, 56...
This article reviews mainstream scientific publications on near-death experiences (NDEs). We searched near-death experience in titles, key words, and abstracts at the Web of Knowledge database published between 1945 and 2013. We identified 266 relevant documents, the oldest from 1977. There was a strong predominance of opinion articles (book reviews, commentaries, and editorials), review...
While there has been a large increase in scientific studies on spirituality, there has been too few of studies of the core of spirituality: spiritual experiences (SE), which often involve altered states of consciousness, reports of anomalous experiences and of consciousness beyond the body. This paper argues that SE, although usually neglected in debates regarding mind-brain relationship (MBR),...
Since spiritual experiences (SE) very often resemble dissociative and psychotic symptoms, there is a risk of misdiagnosis in both directions: labeling a healthy SE as a mental disorder or taking a mental disorder as an SE. There is a scarcity of well-controlled studies on this subject. The paper provides a brief overview of studies on dissociative and psychotic experiences in the non-clinical...
To review research articles in psychiatry and psychology involving Latin American populations and/or produced by Latin American scholars to investigate the differential diagnosis between spiritual/anomalous experiences and mental disorders in order to contribute to the validity of the International Classification of Diseases towards its 11th edition in this area. We searched electronic...
This review discusses the relationships between religion, spirituality, and psychosis. Based on the DSM-IV, we comment on the concept of spiritual and religious problems, which, although they may seem to be psychotic episodes, are actually manifestations of nonpathological spiritual and religious experiences. Studies reporting that hallucinations also occur in the nonclinical population and...
Since ancient times, spiritual beliefs, practices and experiences have been one of the most influential and prevalent components of most societies.Health providers, researchers and the general population have increasingly recognized the importance of the religious/spiritual dimension to health.The number of studies investigating the relationship of spirituality and health has increased...