Schizophrenia Research
July 16, 2024
I. Kreis, T. Lagerberg, K. F. Wold et al.
BACKGROUND Data-driven classification of long-term psychotic symptom trajectories and identification of associated risk factors could assist treatment planning and improve long-term outcomes in psychosis. However, few studies have used this approach, and knowledge about underlying mechanisms is limited. Here, we identify long-term psychotic symptom trajectories and investigate the role of...
Frontiers in Psychology
February 27, 2023
Elisabeth Haug, Merete G Øie, Ingrid H Svendsen et al.
Introduction: Basic self-disorders (SDs) and neurocognitive impairments are fundamental trait-like aspects of schizophrenia spectrum disorders. There has been little research on the association between SDs and neurocognitive impairments in schizophrenia, and no longitudinal studies have investigated if they are related. The aim of this study was to investigate the association between SDs and...
Schizophrenia Research
January 25, 2023
H. M. Ihler, S. H. Lyngstad, E. Gardsjord et al.
OBJECTIVE To investigate the trajectories of diminished expression and apathy over 10 years. Further, to explore the effects of baseline- and persistent cannabis use on the development of diminished expression and apathy during follow-up, while controlling other potential sources and predictors of secondary negative symptoms. METHODS 351 participants with a first episode of non-affective...
Schizophrenia Research
August 25, 2021
H. M. Ihler, T. Lagerberg, S. H. Lyngstad et al.
The association between cannabis use and negative symptoms remains unclear because of inconsistent results in existing studies. In this study we aimed to investigate the association between different aspects of cannabis use and 1) diminished expression and 2) apathy as a two-dimensional model of negative symptoms in a sample of 460 participants with first-episode psychosis. Data were collected...
Frontiers in Psychiatry
July 2, 2020
Attila Szabo, Ibrahim A. Akkouh, Thor Ueland et al.
12 citations
The complex effects of plant cannabinoids on human physiology is not yet fully understood, but include a wide spectrum of effects on immune modulation. The immune system and its inflammatory effector pathways are recently emerging as possible causative factors in psychotic disorders. The present study aimed to investigate whether self-administered cannabis use was associated with changes in...
Schizophrenia Research
December 2018
Ingrid Hartveit Svendsen, Merete G Øie, Paul Møller et al.
Basic self-disturbances (BSDs) are considered core features of schizophrenia spectrum disorders, and are present in the prodromal, early psychotic and chronic phases. Considerable levels of BSDs are also present at first treatment in some patients with psychotic disorders outside the schizophrenia spectrum. There is limited knowledge about the stability of self-disturbances over time. To...