A seven-year longitudinal study of the association between neurocognitive function and basic self-disorders in schizophrenia.
Elisabeth Haug, Merete G Øie, Ingrid H Svendsen, Paul Møller, Barnaby Nelson, Ingrid S. Melle
Frontiers in Psychology February 27, 2023 DOI: 10.3389/fpsyg.2023.1124859 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Longitudinal follow-up study Peer reviewed |
|---|---|
| Sample size | 35 |
| Population | Patients with schizophrenia assessed during their first treatment and about seven years later |
| Duration | 7-year follow-up (mean 7.1 years, SD 0.42) |
| Measures | Examination of Anomalous Self-Experience (EASE) |
| Topics | Philosophy of mind |
| Keywords | Psychoses Executive function Verbal memory Self disturbance |
| Key findings | Poorer executive function at baseline was associated with more basic self-disorders seven years later and with smaller reductions in self-disorders over time. No significant associations were found between self-disorders and other neurocognitive functions such as psychomotor speed or memory. The authors propose that executive impairments in everyday life may affect the development or persistence of self-disorders. |
Abstract
Introduction: Basic self-disorders (SDs) and neurocognitive impairments are fundamental trait-like aspects of schizophrenia spectrum disorders. There has been little research on the association between SDs and neurocognitive impairments in schizophrenia, and no longitudinal studies have investigated if they are related. The aim of this study was to investigate the association between SDs and neurocognitive function in a follow-up study of patients with schizophrenia.
Methods: SDs and neurocognition were examined in 35 patients with schizophrenia during their first treatment and 7 years later (mean 7.1, SD 0.42). SDs were examined with the Examination of Anomalous Self-Experience (EASE) instrument. The neurocognitive examination included assessments of psychomotor speed, executive- and memory functions.
Results: Poorer executive functions at baseline were significantly associated with more SDs 7 years later and smaller reductions in SDs over time. There were no significant associations between other neurocognitive functions and SDs.
Discussion: Executive functions are important for self-regulation, and impairments in these functions in everyday life may have an impact on the development and/or persistence of SDs.
Comparable studies
Other observational and cohort studies on philosophy of mind, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The phenomenology of near-death experiences Subjects who reported near-death experiences | 1980 | Retrospective study | n = 78 |
| Visual Phenomenology of the LSD Flashback Persons with a history of LSD use | 1983 | Observational cohort | n = 123 |
| The neurophenomenology of neutral hypnosis. Individuals of high, medium, and low hypnotizability | 2013 | Observational cohort | n = 37 |
| The Phenomenology of Acute Organic Psychosis Patients with acute organic psychosis and acute schizophrenics | 1987 | Observational cohort | n = 148 |
| EEG oscillatory states as neuro-phenomenology of consciousness as revealed from patients in vegetative and minimally conscious states. Brain-damaged patients with disorders of consciousness and healthy-conscious subjects | 2012 | Observational cohort |
Citations in the library
Cites 12
- Interoceptive inference, emotion, and the embodied self Trends in Cognitive Sciences October 12, 2013
- An Interoceptive Predictive Coding Model of Conscious Presence Frontiers in Psychology 2012
- The neurophenomenology of early psychosis: An integrative empirical study. Consciousness and Cognition November 1, 2019
- Psychopathology of the bodily self and the brain: the case of schizophrenia. Psychopathology 2014
- Altered self-recognition in patients with schizophrenia. Schizophrenia Research April 1, 2020
and 7 more in the library