Skip to content

The Association between Anomalous Self-experiences, Self-esteem and Depressive Symptoms in First Episode Schizophrenia.

Elisabeth Haug, Merete G Øie, Ole A. Andreassen, Unni Bratlien, Kristin L Romm, Paul Møller, Ingrid S. Melle

Frontiers in Human Neuroscience November 7, 2016 DOI: 10.3389/fnhum.2016.00557 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cross-sectional study Peer reviewed
Sample size 55
Population Patients with first-episode schizophrenia spectrum disorders
Measures Examination of anomalous Self-Experience (EASE), Calgary Depression Scale for Schizophrenia (CDSS), Rosenberg Self-Esteem Scale (RSES), Structured Clinical Interview for the Positive and Negative Syndrome Scale (SCI-PANSS), Drug Use Disorder Identification Test (DUDIT), Alcohol Use Disorder Identification Test (AUDIT), Premorbid Adjustment Scale (PAS), Childhood Trauma Questionnaire, short form (CTQ-SF)
Topics Depression
Keywords Schizophrenia Gender differences Self-esteem Childhood trauma First episode psychosis Anomalous self-experiences
Key findings Analyses detected a significant association between current depression and ASEs as measured by the EASE in women, but not in men; the effect of ASEs on depression appeared to be mediated by self-esteem. The authors propose that evaluating ASEs can assist clinicians in understanding patients' experience of self-esteem and depressive symptoms, and that the interaction among ASEs, self-esteem, depression, and suicidality could be a clinical target for preventing suicidality.

Abstract

Background: Anomalous self-experiences (ASEs) aggregate in schizophrenia spectrum disorders, but the relationship between ASEs, and depression has been studied to a limited extent. Lower self-esteem has been shown to be associated with depression in early psychosis. Our hypothesis is that ASEs in early phases of schizophrenia are linked to lower levels of self-esteem, which in turn is associated with depression.

Aim: The aim is to examine the relationship between ASEs, self-esteem and depression in first-episode schizophrenia spectrum disorders.

Method: ASEs were assessed in 55 patients with first-episode schizophrenia by means of the Examination of anomalous Self-Experience (EASE) instrument. Assessment of depression was based on the Calgary Depression Scale for Schizophrenia (CDSS). Self-esteem was measured using the Rosenberg Self-Esteem Scale (RSES). Symptom severity was assessed using the Structured Clinical Interview for the Positive and Negative Syndrome Scale (SCI-PANSS). Substance misuse was measured with the Drug Use Disorder Identification Test (DUDIT), and alcohol use was measured with the Alcohol Use Disorder Identification Test (AUDIT). Data on childhood adjustment were collected using the Premorbid Adjustment Scale (PAS). Data on childhood trauma were collected using the Norwegian version of the Childhood Trauma Questionnaire, short form (CTQ-SF).

Results: Analyses detected a significant association between current depression and ASEs as measured by the EASE in women, but not in men. The effect of ASEs on depression appeared to be mediated by self-esteem. No other characteristics associated with depression influenced the relationship between depression, self-esteem and ASEs.

Conclusion: Evaluating ASEs can assist clinicians in understanding patients' experience of self-esteem and depressive symptoms. The complex interaction between ASEs, self-esteem, depression and suicidality could be a clinical target for the prevention of suicidality in this patient group.

Comparable studies

Other cross-sectional and survey studies on depression, most cited first.

Study Year Design Participants
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety. International sample of people who reported having used a psychedelic 2020 Cross-sectional survey n = 985
The Role of Mindfulness and Psychological Flexibility in Somatization, Depression, Anxiety, and General Psychological Distress in a Nonclinical College Sample Ethnically diverse, nonclinical sample of college undergraduates (76% female) 2011 Observational cross-sectional survey n = 494
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used in a naturalistic group setting is associated with unintended improvements in depression and anxiety. Adults who used 5-MeO-DMT in a group setting with structured procedures 2019 Cross-sectional survey n = 362
Psychological and neuropsychological assessment of regular hoasca users. Regular hoasca users from a U.S. branch of União do Vegetal and matched non-user controls 2016 Cross-sectional study n = 57
Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers Self-selected microdosers and non-microdosers recruited via a mobile application 2021 Cross-sectional survey n = 8,703

Citations in the library

Explore topics