Research Square
October 27, 2026
Chenyu Zhao, Xiaobin Wang, Tongxin He et al.
preprint
Abstract Objective To give a comprehensive review on the effectiveness of mindfulness-based intervention in sports performance in athletes. Methodology Six online databases including Web of Science, EBSCOhost(Elton B. Stephens Company), Cochrane library, Embase, Scopus, Pubmed were searched to identify randomized controlled trials (RCTs) exploring the effects of mindfulness training on...
Research Square
June 22, 2026
Chenyu Zhao, Xiaobin Wang, Wenbo Hao et al.
preprint
Abstract Objectives This study aimed to investigate the effects of brief mindfulness meditation on emotion regulation and its underlying brain functional network mechanisms in college students using functional near-infrared spectroscopy (fNIRS), thereby providing neuroscientific evidence for mindfulness-based interventions targeting emotional health. Method A total of 59 college students were...
Molecular Neurobiology
February 1, 2025
Na Hu, Yujie Zheng, Xueru Liu et al.
7 citations
The abundant expression of circular RNAs (circRNAs) in the central nervous system and their contribution to the pathogenesis of depression suggest that circRNAs are promising therapeutic targets for depression. This study explored the role and mechanism of circKat6b in esketamine's antidepressant effect. We found that intravenous administration of esketamine (5 mg/kg) treatment decreased the...
bioRxiv (Cold Spring Harbor Laboratory)
January 7, 2024
Ziran Huang, Xiaoyan Wei, Xiaobin Wang et al.
3 citations
preprint
Abstract Recent clinical breakthroughs hold great promise for the application of psilocybin in the treatments of psychological disorders, such as depression, addiction, and obsessive-compulsive disorder. Psilocybin is a psychedelic whose metabolite, psilocin, is a 5-HT 2A receptor agonist. Nevertheless, the underlying mechanisms for the effects of psilocybin on the brain are not fully...
Scientific Reports
September 13, 2021
Xin-ping Ouyang, Zhengjia Wang, Mei Luo et al.
To investigate the effects of ketamine on glucose uptake and glucose transporter (GLUT) expression in depressive-like mice. After HA1800 cells were treated with ketamine, 2-[N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino]-2-Deoxyglucose (2-NBDG) was added to the cells to test the effects of ketamine on glucose uptake, production of lactate, and expression levels of GLUT, ERK1/2, AKT, and AMPK....
Psychiatry Research
January 30, 2011
Xiaobin Wang, Yilin Yang, Xian Zhou et al.
Animal and clinical studies have demonstrated that ketamine has quick, obvious and persistent antidepressant-like effect, but such side effects as cardiovascular system excitement and hallucinogenic activity have limited its clinical application. Intravenous anesthetic propofol can remarkably inhibit or eliminate ketamine's side effects including cardiovascular system excitement and...
Ling Qiu, Xuhui Chen, Fu Jia et al.
preprint
Abstract Objective Patients with Postherpetic Neuralgia (PHN) often exhibit depressive-like symptoms, significantly impacting their quality of life. Esketamine, known for its analgesic properties, has also been recognized for its rapid antidepressant effects. However, its efficacy in the treatment of PHN requires further exploration. This study aims to evaluate the impact of intravenous...