arXiv Preprint Archive
October 29, 2026
Jian Wang, Winson F.z. Yang, Wugeng Zheng et al.
preprint
Inferring jhana-type advanced concentration absorption meditation (ACAM-J) states from fMRI data is challenging due to the spatially distributed nature of meditation-related effects, substantial inter-individual variability that can exceed within-subject state differences, and limited sample sizes. Conventional machine-learning approaches often formulate this problem as unimodal, Euclidean,...
CNS Neuroscience & Therapeutics
May 1, 2026
Xuewei Qin, Xuanling Chen, Lan Yao et al.
BACKGROUND: Disorders of consciousness (DoC) present significant therapeutic challenges with limited effective interventions. The choice of anesthetic agent during procedures such as spinal cord stimulation may influence long-term neurological outcomes, yet comparative evidence is scarce. This prospective, non-randomized, comparative effectiveness trial investigated the neurophysiological and...
CNS Neuroscience & Therapeutics
December 1, 2024
Xiaoyu Niu, Yuanyuan Zheng, Wang Wang et al.
7 citations
Esketamine (ESK), a noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, modulates neurotransmitter signaling in the central nervous system. However, the specific mechanisms and therapeutic potential of ESK for intracerebral hemorrhage (ICH) remain unclear. This study aimed to investigate whether ESK promotes nerve repair and improves neurological outcomes in an experimental...
Neural Plasticity
2022
Ming-Hao Yang, Zhi-Peng Guo, Xue-Yu Lv et al.
Rumination is a common symptom of major depressive disorder (MDD) and has been characterized as a vulnerability factor for the onset or recurrence of MDD. However, the neurobiological mechanisms underlying rumination and appropriate treatment strategies remain unclear. In the current study, we used resting-state functional magnetic resonance imaging to investigate the effects of body-mind...
Translational Psychiatry
October 23, 2021
Fangfang Chen, Xueyu Lv, Jiliang Fang et al.
Mindfulness-based interventions such as meditation have increasingly been utilized for the treatment of psychological disorders and have been shown to be effective in the treatment of depression and relapse prevention. However, it remains largely unclear the neural mechanism of the therapeutic effects of meditation among depressed individuals. In this study, we investigated how body-mind...