Lan Hong

2 papers in the library · publishing 2021-2022

Papers

BMRMI Reduces Depressive Rumination Possibly through Improving Abnormal FC of Dorsal ACC.

Neural Plasticity January 1, 2022 Ming-Hao Yang, Zhi-Peng Guo, Xue-Yu Lv et al.

Rumination, a common symptom of major depressive disorder (MDD), may be regulated by a body-mind relaxation meditation induction (BMRMI) intervention through changes in brain connectivity. In 25 people with MDD and 24 healthy controls, resting-state fMRI showed that at baseline, those with MDD had stronger functional connectivity between the right dorsal anterior cingulate cortex (dACC) and right superior frontal gyrus than controls. After the intervention, the MDD group showed weaker connectivity between the left dACC and right middle frontal gyrus, while controls showed enhanced connectivity in the right dACC region. The strength of right dACC-right superior frontal gyrus connectivity correlated positively with rumination scores across all participants at baseline. These findings suggest BMRMI may alter self-referential and cognitive processing by modulating dACC connectivity in MDD with rumination.

DOI: 10.1155/2022/8068988 Full text

Body-mind relaxation meditation modulates the thalamocortical functional connectivity in major depressive disorder: a preliminary resting-state fMRI study.

Translational Psychiatry October 23, 2021 Fangfang Chen, Xueyu Lv, Jiliang Fang et al.

Body-mind relaxation meditation (BMRM) alters thalamocortical functional connectivity in medication-naive adolescents with major depressive disorder (MDD) and healthy controls. Before the intervention, MDD patients showed reduced connectivity between the bilateral precuneus/posterior cingulate cortex and specific thalamus subregions, and increased connectivity between the left occipital thalamus and left medial frontal cortex. After BMRM, these aberrant connections normalized in MDD patients, and both groups showed decreased connectivity between the left rostral temporal thalamus and left inferior occipital region. These changes suggest BMRM may strengthen connections between the thalamus and default mode network, which support attention and self-related processes. The small sample size limits generalizability.

DOI: 10.1038/s41398-021-01637-8 Full text