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María Jesús Álvarez-López

6 papers in the library · publishing 2013-2025

Papers

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Effect of an 18-Month Meditation Training on Telomeres in Older Adults: A Secondary Analysis of the Age-Well Randomized Controlled Trial.

Biological Psychiatry Global Open Science 2025 Perla Kaliman, María Jesús Álvarez-López, Asrar Lehodey et al.

Shorter telomeres are associated with increased risk of cognitive decline and age-related diseases. Developing interventions to promote healthy aging by preserving telomere integrity is of paramount importance. Here, we investigated the effect of an 18-month meditation intervention on telomere length (TL) measures in older people without cognitive impairment. A total of 137 adults age ≥65 years...

Changes in the expression of inflammatory and epigenetic-modulatory genes after an intensive meditation retreat.

Comprehensive Psychoneuroendocrinology August 1, 2022 María Jesús Álvarez-López, Quinn A Conklin, Marta Cosín-Tomás et al.

Meditation retreats are characterized by intensive or concentrated periods of meditation practice, commonly undertaken in a residential setting. Although research indicates that meditation training can positively influence physical and mental health outcomes, the biological consequences of meditation retreat interventions are relatively understudied. In this study, we examined the influence of...

Corrigendum to "Insight meditation and telomere biology: The effects of intensive retreat and the moderating role of personality" [Brain Behav. Immun. 70 (2018) 233-245].

Brain, Behavior, and Immunity August 1, 2018 Quinn A Conklin, Brandon G King, Anthony P Zanesco et al. correction

a Center for Mind and Brain, University of California, Davis, 267 Cousteau Place, Davis, CA 95618, United States Department of Psychology, University of California, Davis, 135 Young Hall, Davis, CA 95616, United States c Department of Biochemistry & Biophysics, University of California, San Francisco, 600 16th St, San Francisco, CA 94158, United States d Center for Neuroscience, University of...

Insight meditation and telomere biology: The effects of intensive retreat and the moderating role of personality.

Brain, Behavior, and Immunity May 1, 2018 Quinn A Conklin, Brandon G King, Anthony P Zanesco et al.

A growing body of evidence suggests that meditation training may have a range of salubrious effects, including improved telomere regulation. Telomeres and the enzyme telomerase interact with a variety of molecular components to regulate cell-cycle signaling cascades, and are implicated in pathways linking psychological stress to disease. We investigated the effects of intensive meditation...

Epigenetic clock analysis in long-term meditators.

Psychoneuroendocrinology November 2017 Raphaëlle Chaix, María Jesús Álvarez-López, Maud Fagny et al.

In this paper, we examined whether meditation practice influences the epigenetic clock, a strong and reproducible biomarker of biological aging, which is accelerated by cumulative lifetime stress and with age-related chronic diseases. Using the Illumina 450K array platform, we analyzed the DNA methylome from blood cells of long-term meditators and meditation-naïve controls to estimate their...

Rapid changes in histone deacetylases and inflammatory gene expression in expert meditators.

Psychoneuroendocrinology November 15, 2013 Perla Kaliman, María Jesús Álvarez-López, Marta Cosín-Tomás et al.

Background: A growing body of research shows that mindfulness meditation can alter neural, behavioral and biochemical processes. However, the mechanisms responsible for such clinically relevant effects remain elusive. Methods: Here we explored the impact of a day of intensive practice of mindfulness meditation in experienced subjects (n=19) on the expression of circadian, chromatin modulatory...