Comprehensive Psychoneuroendocrinology
June 2, 2025
C. Sue Carter
3 citations
The purpose of this narrative review is to examine the hypothesis that two neuropeptides, vasopressin (VP) and oxytocin (OT) and their receptors have central roles in the behavioral and physiological consequences of psychedelic interventions. Transient consequences of psychedelics can include anxiety and in some cases sickness responses such as nausea and vomiting, which may involve VP and...
Comprehensive Psychoneuroendocrinology
November 1, 2024
Robin Blades, Wendy Berry Mendes, Brian P Don et al.
Stress is a driver of depression, and people with depression often struggle to cope with stress and anxiety. This study directly compares the mental health effects of a Wim Hof Method intervention to an active control condition (slow breathing) in women with high stress and high depressive symptoms. We randomized 84 healthy midlife women with high stress and high depressive symptoms to either:...
Comprehensive Psychoneuroendocrinology
February 1, 2023
Daniel Rødbro Burmester, Martin Korsbak Madsen, Attila Szabo et al.
24 citations
Psilocybin is a serotonergic psychedelic that has gained prominent attention recently as a potential therapeutic for neuropsychiatric disorders including Major Depressive Disorder. Pre-clinical and initial studies in humans suggest that serotonin 2A receptor agonists, including serotonergic psychedelics, have anti-inflammatory effects. This may contribute to its therapeutic effects as previous...
Comprehensive Psychoneuroendocrinology
August 1, 2022
Patama Gomutbutra, Tiam Srikamjak, Ladarat Sapinun et al.
The previous metanalysis found that Mind-body intervention (MBI) improves neuropsychologic well-being and may increase brain-derived growth factor (BDNF). BDNF is a neurotrophic factor related to neuroplasticity. To evaluate the effect of the short intensive MBI compared to control-relaxation on Site on BDNF and examine if this change is related to mitochondria function or stress-related...
Comprehensive Psychoneuroendocrinology
August 1, 2022
María Jesús Álvarez-López, Quinn A Conklin, Marta Cosín-Tomás et al.
Meditation retreats are characterized by intensive or concentrated periods of meditation practice, commonly undertaken in a residential setting. Although research indicates that meditation training can positively influence physical and mental health outcomes, the biological consequences of meditation retreat interventions are relatively understudied. In this study, we examined the influence of...
Comprehensive Psychoneuroendocrinology
March 10, 2021
Michaela C. Pascoe, Michael de Manincor, Jana Tseberja et al.
Psychological stressors can lead to distress and result in autonomic arousal and activation of a stress response. Ongoing or persistent stress can disrupt the stress response feedback mechanisms and result in elevated cortisol and pro-inflammatory cytokines which can cause damage to brain regions involved in the regulation of mood and emotion. We propose that the magnitude of the stress...