O presente artigo investiga a constituição ontológica necessária para a ocorrência do sofrimento transformacional, articulando os fenômenos de sintomas de estresse pós-traumático e crescimento pós-traumático com a recente fenomenologia da experiência de possibilidades. A questão central interroga como o ser humano deve estar ontologicamente constituído para que experiências disruptivas possam...
This article examines Tee Yod (Death Whisperer, 2023), a Thai horror film directed by Taweewat Watanawat, through the lens of Buddhist psychology of trauma. Departing from the conventions of the Nang Phi genre, Tee Yod reinterprets the ghost as a metaphor for intergenerational suffering and psychological distress within a Buddhist cosmological and moral framework. Drawing on Theravāda Buddhist...
Veterans face unique mental health challenges, including elevated rates of post-traumatic stress disorder (PTSD), depression, and anxiety, compounded by cultural barriers to traditional therapies. Mindfulness-Based Stress Reduction (MBSR) offers a trauma-informed, non-pharmacological intervention tailored to align with military values. This study employed a repeated-measures design with 4 time...
A recent randomized controlled trial (RCT) did not find an effect of imagery rehearsal therapy (IRT) for nightmares as an add-on to treatment as usual in a sample of trauma-affected refugees. However, certain factors may have accounted for substantial variations in treatment outcomes. This study aimed to test whether symptom severity, cognitive functioning, use of an interpreter, motivation for...
Serotonergic psychedelics produce therapeutic effects in clinical trials of diverse neuropsychiatric disorders, and preclinical models of inflammatory, cardiometabolic, and neuropsychiatric diseases. These effects appear largely mediated by the serotonin 5-HT2A receptor (5-HT2AR). How could psychedelics elicit transdiagnostic therapeutic effects through a single receptor across tissues as...
This scoping review aims to systematically map the neurobiological evidence for psychological and pharmacologically-assisted interventions for post-traumatic stress disorder (PTSD) published between 2020 and 2025. Grounded in the triple-network model (default mode network, salience network, and central executive network), the review will synthesize findings across a range of intervention types,...
Veterans with physical disabilities may experience substantial psychological burden (e.g., PTSD symptoms) and practical barriers to accessing conventional mental health services. VR-assisted meditation could offer a low-threshold alternative, but evidence in this population remains limited. The objective of this study was to examine the feasibility, acceptability and preliminary efficacy of a...
Current neuroscience research calls into question the binary model of anesthesia as a state of consciousness shifted by unconsciousness, replacing it with an idea of consciousness as a continuum created by interactions between large-scale cortex and subcortical regions.Meanwhile, psychedelic drugs are making a comeback as potential treatments for treatment-resistant depression, post-traumatic...
Ketamine-Assisted Therapy (KAT) presents a promising alternative for addressing mental health challenges, particularly in treatment-resistant conditions, yet little exists in the literature guiding its implementation in an Indigenous context, for Indigenous participants, or describing culturally adapted delivery models. This paper presents insights and lessons learned from a collaborative pilot...
Posttraumatic stress disorder (PTSD) is associated with elevated inflammation and risk for chronic illness, yet few studies have examined inflammatory biomarker outcomes of PTSD interventions. Rapid PTSD symptom reduction has been observed following 3,4-methylenedioxymethamphetamine (MDMA)-assisted therapy, which leverages MDMA as a prosocial adjunct to psychotherapy. No studies have evaluated...