Progress in Palliative Care
July 3, 2024
A. C. Garcia, Myla Chistie Araujo Custodio Bonifácio, L. O. Maia
The scientific community's interest in psychedelic-assisted therapies (PAT) as a potential new therapeutic modality is growing, as evidence suggests that their use has a significant impact on the outcomes of patients with various conditions, including those with serious illnesses. In the context of PAT, the interpersonal bond established between patient and therapist is a vital factor for the...
Journal of Psychoactive Drugs
July 3, 2024
Bruno Romeo, Ewen Kervadec, Baptiste Fauvel et al.
5 citations
Treating cannabis use disorder remains a significant challenge in the field of addiction medicine. Some recent studies point to psychedelic-assisted psychotherapy as a potential treatment option for substance use disorders. The objective of this study was therefore to explore the impact of naturalistic psychedelic experiences on cannabis use and psychological flexibility. An online...
npj Mental Health Research
July 2, 2024
Maryam Golafshani, Daniel Z. Buchman, Muhammad Ishrat Husain
3 citations
Given the renewed interest in the use of psychedelics for the treatment of mental and substance use disorders in recent decades, there has also been renewed discussion and debate about whether it is necessary or beneficial for those who study and deliver psychedelic-assisted psychotherapy (PAP) to have had personal experience of using psychedelics. This paper provides a brief history of this...
Sleep Medicine
July 1, 2024
Andreas S Lappas, Eleni Glarou, Zoi A Polyzopoulou et al.
13 citations
Sleep disturbances are an important symptom dimension of post-traumatic-stress-disorder (PTSD). There is no meta-analytic evidence examining the effects of all types of pharmacotherapy on sleep outcomes among patients with PTSD. Medline/Embase/PsychInfo/CENTRAL/clinicaltrials.gov/ICTRP, reference lists of published reviews and all included studies were searched for Randomised Controlled Trials...
Journal of Pakistan Psychiatric Society
June 30, 2024
Nauman Ashraf
1 citation
Psychedelics, substances known to alter perception, mood, and consciousness, have been used across various cultures for centuries, often in religious ceremonies to facilitate spiritual experiences. Lysergic acid diethylamide (LSD) was used clinically from the 1950s until its ban in 1967. Recently, there has been a resurgence of interest in psychedelics for treating mental health disorders such...
Folia Pharmacologica Japonica
June 30, 2024
Daisuke Ibi
1 citation
Major Depressive Disorder (MDD) poses a significant global health burden, with 30-40% patients developing resistance to standard clinical antidepressants, such as selective serotonin reuptake inhibitors and tricyclic antidepressants. In 2016, Carhart-Harris and colleagues reported that psilocybin, the hallucinogenic compound derived from magic mushrooms, exhibits rapid and enduring...
Journal of Psychoactive Drugs
June 27, 2024
Tonći Mastelić, Tonka Borovina Marasović, M. Žuljević et al.
ABSTRACT For some time now, there has been an increased interest in psychedelics among scientists and mental health experts. Given that experts introduce therapy and advise patients, it is important to know their views. Therefore, the aim of our research was to examine and compare the attitudes of psychiatrists and psychologists toward psychedelics. We were interested in how they are formed and...
Pharmaceuticals
June 27, 2024
Haron Avgana, Roni Shira Toledano, Irit Akirav
8 citations
MDMA-assisted psychotherapy has shown potential as an effective treatment for post-traumatic stress disorder (PTSD). Preclinical studies involving rodents have demonstrated that MDMA can facilitate the extinction of fear memories. It has been noted that MDMA impacts oxytocin neurons and pro-inflammatory cytokines. Thus, the aim of this study was to explore the role of oxytocinergic signaling...
Psychodynamic Practice
June 24, 2024
Christopher W. T. Miller
1 citation
There has been a renewed interest in the clinical applications of psychedelics, with increasing use for a variety of psychiatric conditions. Individuals often describe psychedelic sessions as among the most significant experiences in their lives, emphasising the sense of awe, connectedness, and spiritual transformation they undergo. They can also feel they are experiencing truth and becoming...
Psychedelics
June 14, 2024
N. Garel
Dr Nicolas Garel is an Assistant Professor in the Department of Psychiatry and Addictology at the University of Montreal and a junior investigator at the Research Center of the Centre Hospitalier de l'Université de Montréal. Dr Garel did his psychiatry residency at McGill University before completing the Clinician-Investigator Program and a Master's degree at McGill University, studying the...