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Psilocybin: all studies

Page 238 of 439: studies 2,371 to 2,380 of 4,389, newest first. Back to the psilocybin overview

Research

Classic psychedelics do not affect T cell and monocyte immune responses.

Frontiers in Psychiatry 2023 Deborah Rudin, Alexander Areesanan, Matthias E. Liechti et al. 9 citations

Classic psychedelics have been shown to exert therapeutic potential for the treatment of various psychiatric disorders, neuropsychiatric diseases, and neuronal damage. Besides their psychopharmacological activity, psychedelics have been reported to modulate immune functions. There has thus far been a sparse exploration of the direct immune-modulating effect of psychedelics on human immune cells...

Psychedelics, entropic brain theory, and the taxonomy of conscious states: a summary of debates and perspectives.

Neuroscience of Consciousness 2023 Sidath Rankaduwa, Adrian M. Owen 21 citations

Given their recent success in counseling and psychiatry, the dialogue around psychedelics has mainly focused on their applications for mental health. Insights from psychedelic research, however, are not limited to treating mental health, but also have much to offer our current understanding of consciousness. The investigation of psychedelic states has offered new perspectives on how different...

DOI: 10.1093/nc/niad001 (opens in new tab) Full text (opens in new tab) Psilocybin Disorders of consciousness Entropic brain theory Psychedelic states +9

Corrigendum: Three naturally-occurring psychedelics and their significance in the treatment of mental health disorders.

Frontiers in Pharmacology 2023 Nataliya S. Vorobyeva, Alena A. Kozlova 1 citation correction

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"How Do I Learn More About this?": Utilization and Trust of Psychedelic Information Sources Among People Naturalistically Using Psychedelics.

Journal of Psychoactive Drugs 2023 Daniel J. Kruger, Oskar Enghoff, Moss Herberholz et al. 24 citations

There is a surge of interest in psychedelics, including new stakeholders and greater media attention. There is a need to examine the information-seeking behavior of people using psychedelics naturalistically, given the importance of preparation and harm-reduction. We examined sources of information for people using psychedelics naturalistically, and the degree to which they are trusted in a...

The psychedelic afterglow phenomenon: a systematic review of subacute effects of classic serotonergic psychedelics

Therapeutic Advances in Psychopharmacology 2023 Ricarda Evens, Tomislav Majić, Timo Torsten Schmidt et al. 49 citations

Background: Classic serotonergic psychedelics have anecdotally been reported to show a characteristic pattern of subacute effects that persist after the acute effects of the substance have subsided. These transient effects, sometimes labeled as the ‘psychedelic afterglow’, have been suggested to be associated with enhanced effectiveness of psychotherapeutic interventions in the subacute period....

Functional MRI markers for treatment-resistant depression: Insights and challenges.

Progress in Brain Research 2023 Vasileia Kotoula, Jennifer W. Evans, Claire Punturieri et al. 17 citations

Imaging studies of treatment-resistant depression (TRD) have examined brain activity, structure, and metabolite concentrations to identify critical areas of investigation in TRD as well as potential targets for treatment interventions. This chapter provides an overview of the main findings of studies using three imaging modalities: structural magnetic resonance imaging (MRI), functional MRI...

Next generation antidepressants with novel mechanisms for treatment resistant depression.

Progress in Brain Research 2023 Mu-Hong Chen, Pei-Chi Tu, Tung-Ping Su 3 citations

Evidence has suggested that the modulation of N-methyl-d-aspartate receptors (NMDARs) and 5-hydroxytryptamine receptors (5-HTRs) via the psychedelic drugs, such as ketamine and psilocybin, rapidly alters the state of consciousness and the neuroplasticity. The United State Food and Drug Administration approved the indications of esketamine for treatment-resistant depression (TRD) in 2019 and...

Systematic review and rationale of using psychedelics in the treatment of cannabis use disorder.

Frontiers in Psychiatry 2023 Angela N Phan, Garth E Terry 6 citations

Cannabis use disorder (CUD) is prevalent in ~2-5% of adults in the United States and is anticipated to increase as restrictions to cannabis decrease and tetrahydrocannabinol (THC) content in cannabis products increase. No FDA-approved medications for CUD are currently available, despite trials of dozens of re-purposed and novel drugs. Psychedelics have garnered interest as a therapeutic class...

The Resurgence of Hallucinogen Drugs in Clinical Research.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2023 María T Rivera-García, Silvia L. Cruz 8 citations

Since the dawn of civilization, ancient cultures have utilized hallucinogens from plants and fungi in the context of religious and healing practices. Recently, their use has expanded to other cultures. Hallucinogens are natural or synthetic substances that alter the perception of reality at nontoxic doses, producing intense psychological and physiological effects. The initial research on...

Altered states of leadership: mindfulness meditation, psychedelic use, and leadership development.

Frontiers in Psychology 2023 Otto Simonsson, Cecilia U.D. Stenfors, Simon B. Goldberg et al. 4 citations

Previous research suggests that mindfulness meditation and psychedelic substances show promise as mental health interventions, but relatively little remains known about their potential impact on leadership outcomes. This study aimed to investigate if and how mindfulness meditation and psychedelic use may impact leadership among respondents with a management position as their primary role at...