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Silvia L. Cruz

2 papers in the library · 18 citations · publishing 2023

Papers

First drug-checking study at an electronic festival and fentanyl detection in the central region of Mexico

Harm Reduction Journal December 10, 2023 Silvia L. Cruz, Miguel Bencomo-Cruz, María E. Medina-Mora et al. 10 citations

At an outdoor electronic music festival near Mexico City, 40 young adults (mostly single men aged 22–48) provided 51 drug samples for voluntary, confidential testing. Most samples contained the expected drug plus adulterants such as methylene-dioxy-ethyl-amphetamine, methylene-dioxy-propyl-amphetamine, hydroxyamphetamine, and the antidepressant venlafaxine. Fentanyl was detected in 2 of 4 cocaine samples and in 14 of 22 MDMA samples. These adulterants, especially fentanyl and amphetamine-like substances, pose serious health risks. The authors urge monitoring of adulterants at festivals and call for prevention, treatment, and harm reduction policies in Mexico, including naloxone distribution and drug-assisted therapies.

The Resurgence of Hallucinogen Drugs in Clinical Research.

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion January 1, 2023 María T Rivera-García, Silvia L. Cruz 8 citations

Classic hallucinogens such as LSD, dimethyltryptamine, psilocin, and mescaline have chemical structures similar to serotonin and directly activate 5-HT2A receptors. Ketamine, a dissociative anesthetic, has antagonist effects at the glutamatergic N-methyl-D-aspartate receptor and indirectly activates 5-HT2A receptors. Ketamine shows rapid antidepressant effects and reduces suicidal ideation, but these effects are short-lasting. Other hallucinogens are under study. The review calls for continued research with more rigorous methodology and inclusion of long-term effects.