N,N-Dimethyltryptamine (DMT) is an endogenous serotonergic psychedelic capable of producing radical shifts in an experience that have significant implications for consciousness and its neural correlates, especially given the "disconnected consciousness" suggested by the "breakthrough" DMT state. Its increasing usage and clinical trial indicate the growing importance of a thorough elucidation of...
Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a lifetime of chronic disability, causing devastating personal and economic consequences. Developing new treatments for PSD remains a challenge, particularly those that target its core cognitive deficits. A key barrier to progress is the tenuous link between the basic neurobiological understanding of PSD and its...
Abstract Consumption of the psychedelic brew ayahuasca is a central ritualistic aspect of the Santo Daime religion. The current observational, baseline controlled study was designed to assess whether members (n = 24) of the Santo Daime church would show enhanced capacity for mental imagery during an ayahuasca experience. In addition, this study assessed whether the effects of ayahuasca on...
There is growing scientific evidence for the therapeutic benefits of the Amazonian plant-based psychedelic "ayahuasca" for neuropsychiatric disorders such as depression and anxiety. However, there are certain challenges when incorporating botanical ayahuasca into biomedical research and clinical therapy environments. Formulations inspired by ayahuasca, which contain specific and standardized...
The study of consciousness is a long-standing central challenge in the relationship between the brain and the mind. One key step towards understanding consciousness is to empirically narrow down neural processes associated with the subjective experience of a particular content (neural reductionism). The fundamental methodological problem in consciousness research is the subjectivity of the...
Indrajāla is the concept of universal holographic interrelationship which relates to energy, consciousness and continuity of universal multidimensional processes. This concept is related to Vedic Cosmology which denies separateness in the universe. This article describes the concept of Indrajāla in the Vedas which later became the central doctrine in Buddhism. This concept has great...
Near-death experiences (NDEs) can occur during episodes of unconsciousness from life-threatening conditions, such as sudden cardiac arrests (SCAs). This study is based on interviews with patients who had an NDE. The interviews were analyzed with phenomenological hermeneutical method for their lived experiences and the meaning for the view of life and death. Four participants were interviewed 10...
Jagna Brudzińska's Bi-Valenz der Erfahrung: Assoziation, Imaginäres und Trieb in derGenesis der Subjektivität bei Husserl und Freud is the first book-length study 1 to investigate the relationship of phenomenology and psychoanalysis from the perspective of Edmund Husserl's genetic philosophy. 2 The book addresses scholars of philosophy and psychology who wish to gain a deeper understanding of...
Within the clinical framework of a case of schizophrenic psychosis confronted with the lockdown, some destabilizing discoveries of quantum mechanics and its implications in neuroscience and psychoanalysis are introduced. Through fractal logic, the Author attempts attempt to understand on the one hand the relationship between microscopic phenomena and macroscopic processes of the psyche and on...
Objective: The aim of this study was to assess the results of all meta-analyses on anomalous cognition conducted between 1989 and 2021 in order to find moderators associated with greater effect sizes. Method: We included all meta-analyses of studies related to anomalous cognition published up to 2021. Results: Our dataset, accumulated over more than 80 years of investigation, refers to 11...