Orexin can induce arousal from general anaesthesia; however, the underlying mechanisms are not fully understood. Nucleus accumbens (NAc), a downstream target of orexinergic neurones, plays a role in regulating consciousness. We aimed to clarify whether and how the NAc mediates the arousal effects of orexin. Fibre photometry was used to track changes of orexinergic afferent activity during...
Does consciousness have non-instrumental aesthetic value? This paper answers this question affirmatively by arguing that consciousness is sublime. The argument consists of three premises. (1) An awe experience of an object provides prima facie justification to believe that the object is sublime. (2) I have an awe experience about consciousness through introspecting three features of...
The technological advances and material control that have resulted from reductive and deterministic practices of science are quite real. The digitally mediated expansion of experiential freedoms-of-choice and the transformative problem-solving potential of artificial intelligence are undeniable. But for all its successes, reductive physicalism has failed to solve the so-called hard problem of...
Objective. Unwanted meditation-related experiences commonly occur and alternate with positive experiences over time. So far, effects have been studied as discrete events, creating difficulties to predict challenging experiences. We explored meditation experiences through a developmental lens, investigating whether a modern interpretation of the Stages of Insight (SoI), a Buddhist model of...
Studies have not explored consciousness during deep hypothermic circulatory arrest (DHCA). However, as studies in cardiac arrest have identified a spectrum of consciousness, we sought to establish the feasibility of studying consciousness during DHCA. This was a prospective study across 10 hospitals with 36 DHCA patients undergoing thoracic aortic aneurysm repair or pulmonary endarterectomy. A...
The objective of this study is to conduct a comprehensive review literature researches examining the relationships between therapist mindfulness and the therapeutic alliance and therapeutic relationship. To this end, articles published on the subject between 2006 and 2024 were identified through a search databases PubMed, Web of Science, Medline, Taylor & Francis Online, Science Direct, Turkish...
This article explores the complexity of conveying subjective experience through language. An essential aspect of this topic is the definition of subjectivity which reflects the uniqueness of each individual’s inner world. Subjectivity denotes that every person’s experience is individual, shaped by personal memories, emotions, and worldview. Often, this experience is difficult to communicate to...
To evaluate the efficacy of short-term spinal cord stimulation (stSCS) in promoting tracheal decannulation among patients with brain injury-induced disorders of consciousness(DoC). A retrospective cohort study was conducted on 81 tracheotomized brain injury patients with DoC treated at Ganzhou People's Hospital between June 2021 and June 2022.Patients were divided into two groups: the stSCS...
The mechanisms underlying consciousness and its potential continuity beyond biological death remain pivotal challenges in neuroscience. This study integrates quantum biology, Buddhist psychology, and thought experiments to propose a novel framework in which consciousness persists through hypothetical particles. Using three hypothetical scenarios—brain revival, molecular disassembly/reassembly,...
Kamala Das has always been vocal about the pain and suffering of the women in contemporary times. Her frankness in dealing with the taboo topics of the society invited unwanted controversies for her. The short stories of Kamala Das mostly speak about the uninhibited desires of the females who often face apprehensive behaviour for having their own ideas of sexuality. The paper is an attempt to...