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BMC Neuroscience

ISSN 1471-2202

10 papers in the library · 1,817 citations · publishing 2004-2026

Papers

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Ibogaine induces juvenile-like plasticity and modulates functional and structural regulators of plasticity in the adult mouse visual cortex.

BMC Neuroscience May 13, 2026 Alejo Acuña, Federico Billeri, Valentino Totaro et al.

Psychedelics have emerged as powerful modulators of neural plasticity, yet whether the atypical psychedelic ibogaine can enhance plasticity remains poorly understood. Here, we investigated whether a single administration of ibogaine can reinstate juvenile-like experience-dependent plasticity in the adult mouse visual cortex, a canonical model for studying neuroplasticity. Adult mice were...

Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice

BMC Neuroscience March 24, 2026 Michael Fiorillo, Javier González-Maeso

BACKGROUND: Neuroinflammation is a hallmark of numerous neuropsychiatric and neurodegenerative disorders. Psychedelics have garnered recent attention for their anti-inflammatory and neuroprotective effects. However, it remains unknown whether they can prophylactically prime immune pathways to prevent subsequent neuroinflammatory responses, and whether such effects depend on serotonin 5-HT2A...

The short-term spinal cord stimulation improves the rates of tracheal decannulation in patients of brain injury with disorders of consciousness.

BMC Neuroscience May 26, 2025 Guanlin Huang, Dong Wang, Qiang Chen et al. 1 citation

To evaluate the efficacy of short-term spinal cord stimulation (stSCS) in promoting tracheal decannulation among patients with brain injury-induced disorders of consciousness(DoC). A retrospective cohort study was conducted on 81 tracheotomized brain injury patients with DoC treated at Ganzhou People's Hospital between June 2021 and June 2022.Patients were divided into two groups: the stSCS...

Dance as mindful movement: a perspective from motor learning and predictive coding.

BMC Neuroscience November 6, 2024 W Tecumseh Fitch, Rebecca Barnstaple 9 citations

Defining "dance" is challenging, because many distinct classes of human movement may be considered dance in a broad sense. Although the most obvious category is rhythmic dancing to a musical beat, other categories of expressive movement such as dance improvisation, pantomime, tai chi, or Japanese butoh suggest that a more inclusive conception of human dance is needed. Here we propose that a...

Neuroprotective effects of psilocybin in a rat model of stroke.

BMC Neuroscience October 8, 2024 Seong-Jin Yu, Kuo-Jen Wu, Yu-Syuan Wang et al. 8 citations

Psilocybin is a psychedelic 5HT2A receptor agonist found in "magic mushrooms". Recent studies have indicated that 5HT2A agonists, such as dimethyltryptamine, given before middle cerebral artery occlusion (MCAo), improve staircase behavior, increased BDNF expression, and reduce brain infarction in stroke rats. The objective of this study is to determine the protective effect of psilocybin in...

Modulation of long-term potentiation following microdoses of LSD captured by thalamo-cortical modelling in a randomised, controlled trial.

BMC Neuroscience February 5, 2024 Robin J Murphy, Kate Godfrey, Alexander D Shaw et al. 16 citations

Microdosing psychedelics is a phenomenon with claimed cognitive benefits that are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing effects on neuroplasticity, which cannot be measured directly in humans, but may be indexed by non-invasive electroencephalography (EEG) paradigms. This study used a visual long-term potentiation (LTP) EEG paradigm to test the...

Monitoring the neural activity associated with praying in Sahaja Yoga meditation.

BMC Neuroscience November 13, 2023 Oscar Perez-Diaz, Alfonso Barrós‐loscertales, Uffe Schjoedt et al.

Sahaja Yoga Meditation draws on many religious traditions and uses a variety of techniques including Christian prayer to reach a state known as thoughtless awareness, or mental silence. While there are many studies on the neural correlates of meditation, few studies have focused on the neural correlates of praying. Thus, the aim of our research was to study the neural activity associated with...

Effects of nitric oxide-related compounds in the acute ketamine animal model of schizophrenia

BMC Neuroscience March 5, 2015 Ludmyla Kandratavicius, Priscila Alves Balista, Daniele C. Wolf et al. 40 citations

BACKGROUND: Better treatments for schizophrenia are urgently needed. The therapeutic use of the nitric oxide (NO)-donor sodium nitroprusside (SNP) in patients with schizophrenia has shown promising results. The role of NO in schizophrenia is still unclear, and NO modulation is unexplored in ketamine (KET) animal models to date. In the present study, we compared the behavioral effects of pre-...

Extensive neuroadaptive changes in cortical gene-transcript expressions of the glutamate system in response to repeated intermittent MDMA administration in adolescent rats

BMC Neuroscience April 17, 2008 Anna M.s. Kindlundh-Högberg, Anna Blomqvist, Rana Malki et al. 40 citations

Repeated intermittent MDMA administration induces neuroadaptive changes in gene-transcript expressions of glutamatergic NMDA and AMPA receptor subunits, metabotropic receptors and transporters in regions of the brain regulating reward-related associative learning, cognition, and memory and neuro-endocrine functions.

An information integration theory of consciousness

BMC Neuroscience November 2, 2004 Giulio Tononi 1,703 citations

BACKGROUND: Consciousness poses two main problems. The first is understanding the conditions that determine to what extent a system has conscious experience. For instance, why is our consciousness generated by certain parts of our brain, such as the thalamocortical system, and not by other parts, such as the cerebellum? And why are we conscious during wakefulness and much less so during...