Classical psychedelics such as N,N -dimethyltryptamine (DMT) modulate consciousness via serotonergic receptor agonism, and are increasingly investigated for their psychotherapeutic potential. When combined with the monoamine oxidase A (MAO-A) inhibitor harmine—mimicking the pharmacological profile of ayahuasca—oral DMT induces a psychedelic experience lasting 4–5 h. While some neuroimaging...
Serotonergic psychedelics are known for their profound effects on consciousness and are gaining renewed interest as potential psychiatric treatments. These advances underscore the need to clarify the mechanisms of action of these compounds. This systematic review compiles and critically evaluates 23 in vitro and 26 in vivo electrophysiological studies on psychedelic compounds, with an emphasis...
Classical psychedelics such as N,N-dimethyltryptamine (DMT) modulate consciousness via serotonergic receptor agonism, and are increasingly investigated for their psychotherapeutic potential. When combined with the monoamine oxidase A (MAO-A) inhibitor harmine-mimicking the pharmacological profile of ayahuasca-oral DMT induces a psychedelic experience lasting 4-5 h. While some neuroimaging...
Modern society is increasingly affected by lifestyle-related disorders such as obesity, stress, anxiety, cognitive fatigue, hypertension, poor respiratory health, and sedentary living patterns. The rising prevalence of these conditions has created a growing demand for low-cost, time-efficient, and easily accessible preventive wellness systems that can simultaneously support physical health,...
This study examines the complex interplay between ecology and spirituality in Africana Indigenous Religions (AIRs), emphasising the influence of sacred worldview on environmental ethics and practices. The main aim is to investigate how AIRs perceive nature as a living, sacred entity, and how this worldview influences ecological stewardship, biodiversity preservation, and sustainable practices....
Shreemad Bhagwat Geeta is one of the great spiritual writings which one can locate among the Indian spiritual writings. Shreemad Bhagwat Geeta may be considered as a path director in many fields. This is one of the most pious and holistic spiritual writing. Quantum mechanics, though is the development of last century and has approximately 100-125 years of its development. This mechanics is...
Background: This study aimed to examine the relationships among dream themes, coping attitudes, and emotional authenticity. Dreams may serve as important phenomenological indicators reflecting individuals’ emotional processes and coping patterns in waking life. Methods: Using a quantitative correlational survey design, data were collected from 555 participants through the Dream Themes Scale...
This study theoretically explores the psychotherapeutic mechanisms of Holotropic Breathwork, an experiential technique developed by Stanislav and Christina Grof, by employing Charles T. Tart's model of altered states of consciousness as a theoretical framework. Through literature review and conceptual analysis, Tart's three conditions of state transition (set, setting, and trigger) and his...
The pursuit of understanding the enigma that is the relationship between humanity and the universe is as ancient as humanity itself. Different methods were employed by enlightened scholars to resolve the mystery of the nature and living beings in a rational manner, which led to the development of various belief systems and branches of knowledge. Physics, one of the various disciplines of...
The recent developments in artificial intelligence (AI), particularly in light of the impressive capabilities of transformer-based Large Language Models (LLMs), have reignited the discussion in cognitive science regarding whether computational devices could possess semantic understanding or whether they are merely mimicking human intelligence. Recent research has highlighted limitations in...