Neuroplasticity: all studies (page 67) - The Consciousness Library

Esketamine in Treatment-Resistant Depression: Clinical and Translational Perspectives.

Current Neuropharmacology July 22, 2026

Esketamine in Treatment-Resistant Depression: Clinical and Translational Perspectives.

DOI: 10.2174/011570159x465328260703100233

Personalized non-invasive combined magnetic and electrical stimulation of the default mode network in mild AD patients (CMES-AD): a multicentric randomized sham-controlled trial protocol.

Alzheimer's Research & Therapy July 21, 2026 Sonia Bonnì, Romina Esposito, Lucia Mencarelli et al.

Patients with Alzheimer's disease (AD) exhibit early alterations in the Default Mode Network (DMN), a key brain network involved in episodic memory where the precuneus plays a central role. Precision-targeted, non-invasive brain stimulation represents a promising strategy to improve cognitive function in individuals with dementia. The DMN can be modulated through personalized non-invasive...

DOI: 10.1186/s13195-026-02145-x Full text Default mode network Alzheimer's disease Precuneus Itbs +1

Sustained abstinence in severe ketamine use disorder following ibogaine treatment case report

Frontiers in Psychiatry July 20, 2026 Sergio Pérez Rosal, Sonya C. Faber, Markus Backmund

Substance use disorders (SUD) involving ketamine, cocaine, and alcohol present significant clinical challenges, often characterized by high relapse rates and limited pharmacological options. This case report details a 30-year-old male with a five-year history of severe polysubstance dependence, including daily intranasal ketamine use (2–3 g/day), cocaine, and alcohol, comorbid with recurrent...

DOI: 10.3389/fpsyt.2026.1846320

Yoga, Meditation, and Breathing Techniques on Stress and Anxiety : A Systematic Literature Review and a Proposal for an Integrated Neurosomatic Mental Health Model

Zenodo (CERN European Organization for Nuclear Research) July 19, 2026 Gönültaş Gökben preprint

The Effects of Yoga, Meditation, and Breathing Techniques on Mental Health: A Systematic Literature Review and Proposal for an Integrated Neurosomatic Mental Health Model Mental health problems associated with stress, anxiety, and reduced psychological well-being have become increasingly prevalent worldwide, highlighting the need for innovative and integrative approaches in mental health care...

DOI: 10.5281/zenodo.21435963 Anxiety Mental health Psychological intervention Systematic review +9

Psychedelic Therapies in the Management of Post-Traumatic Stress Disorder

Journal of Education, Health and Sport July 16, 2026 Jakub Bajer, Aleksandra Włodarczyk, Hubert Kulawinek et al.

Background. Post-Traumatic Stress Disorder (PTSD) is an important public health challenge typically treated with trauma-focused psychotherapy and Selective Serotonin Reuptake Inhibitors (SSRIs). However, high rates of residual symptoms associated with these standard treatments have led to a renewed interest in psychedelic-assisted therapies. Aim. This review attempts to examine emerging...

DOI: 10.12775/jehs.2026.94.73071 Traumatic stress Ketamine Psilocybin Anxiety disorder +5

Serum brain-derived neurotrophic factor following oral esketamine in treatment-resistant depression: Results from a randomized placebo-controlled trial.

Journal of Affective Disorders July 16, 2026 Sara Massetti, Sanne Y Smith-Apeldoorn, Jolien K E Veraart et al.

Ketamine and its enantiomer esketamine are efficacious in 30-35% of the patients with treatment-resistant depression (TRD). Increased serum brain-derived neurotrophic factor (BDNF) following treatment has been proposed as a potential biomarker of antidepressant response. This is based on studies evaluating single intravenous ketamine treatment. BDNF expression at different treatment schedules...

DOI: 10.1016/j.jad.2026.122265 Full text Esketamine Major depressive disorder Brain-derived neurotrophic factor Clinical trial

Integrated 5-HT2A-TrkB and G protein signaling in serotonergic psychedelic responses.

Molecular Psychiatry July 16, 2026 Marco Taddei-Tardón, Lidia Medina-Rodríguez, Jessica L Maltman et al.

Serotonergic psychedelics have attracted considerable interest as promising therapeutic agents. However, the molecular mechanisms linking their acute hallucinogenic-like effects to longer-lasting neuroplastic responses remain incompletely understood, partly because of the scarcity of native neural models suitable for mechanistic studies. Here, we developed a neural stem cell-derived in vitro...

DOI: 10.1038/s41380-026-03746-6 Full text

ESTRESSE E ECOANSIEDADE NA FORMAÇÃO MÉDICA UNIVERSITÁRIA: UM ESTUDO DESCRITIVO BASEADO NOS BENEFÍCIOS DO PROJETO MEDITA-AÇÃO

Revista Tópicos July 15, 2026 Tiago Fontes Amorim, Andréa Cristina de Sousa, Andresa de Cássia Martini et al.

O adoecimento mental entre estudantes de Medicina, caracterizado por elevados níveis de estresse e ansiedade, tem sido agravado pela emergência da ecoansiedade no contexto das crises climáticas e ecológicas globais. Este trabalho analisa os efeitos de práticas contemplativas na saúde mental e na consciência ecológica de graduandos de Medicina, utilizando como base a experiência do projeto de...

DOI: 10.70773/revistatopicos/783618618 Full text Context archaeology Mental illness Work physics Depression economics

Entropy, the Paradoxical Predicate of Order, Mind, and the Intellectual Beauty of Discovered Truth

Metrics July 15, 2026 Richard J. DiRocco, Sonia F. Pearson, Edgar E. Coons

We present a unifying thesis which posits that the biological resolution of uncertainty is a fundamental adaptation to entropy’s negative impact on the highly ordered molecular structures required to maintain the living state. These molecular biological adaptations are highly conserved and play a critical role in the survival of the earliest multicellular organisms and the vertebrates...

DOI: 10.3390/metrics3030015 Beauty Ambiguity Embodied cognition Contingency +6

The potential role of psychedelics in palliative care

Medycyna Paliatywna July 15, 2026 Maciej Sulerzycki, Katarzyna Pomykała, Katarzyna Giemza et al.

In recent years, there has been a growing interest in the therapeutic use of psychedelics. In palliative medicine, they are being considered as an alternative approach to treating depression, existential distress, and chronic pain conditions. This review presents current literature on the use of psychedelic substances such as psilocybin, lysergic acid diethylamide,...

DOI: 10.5114/pm.2025.154446 Full text Depression Palliative care Psychedelics Existential distress.