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MDMA: all studies

Page 250 of 346: studies 2,491 to 2,500 of 3,454, newest first. Back to the MDMA overview

Research

The purpose of the psychosocial protocol in the psychedelic-assisted therapy: A scoping review

Journal of Psychopharmacology June 26, 2026 Flavia Giaffone de Paiva Ferreira, João Ariel Bonar Fernandes, Renato Filev et al.

With growing research on the use of psychedelics to treat mental health conditions, greater attention to the psychosocial procedures accompanying substance administration is warranted. This scoping review aims to categorize psychosocial protocols used in research involving psychedelics as psychiatric treatment according to their purpose, denomination, format, therapeutic orientation,...

DOI: 10.1177/02698811261453850 (opens in new tab) Psychosocial Categorization Observational study Flexibility engineering +15

Psychedelics and autism spectrum disorder: Mechanistic insights, translational evidence and ethical challenges

Journal of Psychiatric Research June 23, 2026 Júlio César Claudino Dos Santos, Sofia Januário Bolan, Guilherme Lodetti da Silva et al.

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental condition characterized by persistent deficits in social communication and interaction, restricted and repetitive patterns of behavior, and sensory processing alterations, frequently accompanied by anxiety, emotional dysregulation, and other psychiatric comorbidities. Despite advances in behavioral and pharmacological...

DOI: 10.1016/j.jpsychires.2026.06.035 (opens in new tab) Autism spectrum disorder Medline Spectrum functional analysis Poison control +3

Delineating Socio-Behavioural Patterns, Community Dynamics and Health Impacts associated with Chemsex among Men who have sex with Men in New Delhi.

Przeglad epidemiologiczny June 19, 2026 Atul Shendge, Abhishek Royal, Vaibhav Kumar et al.

Chemsex, involving intentional psychoactive substance use to enhance sexual experiences, poses significant health risks to men who have sex with men (MSM). In India, limited research exists on chemsex dynamics within MSM communities, particularly in stigmatized urban settings like New Delhi. This study explored socio-behavioural patterns, community dynamics, and health impacts associated with...

DOI: 10.32394/pe/219308 (opens in new tab) Full text (opens in new tab) Chemsex Mental health Sexual behaviour Substance use

Psychedelic Use, Microdosing, Motives, and Information and Product Sources Among Young Adults in the United States

Journal of Psychoactive Drugs June 19, 2026 Carla J. Berg, Darcey M. Mccready, Cassidy R Loparco et al.

= 26.38, ~50% past-month cannabis use by design) completed an online survey. Multivariable regression assessed sociodemographics, mental health, and adverse childhood events (ACEs) in relation to: (1) past-year psychedelic use; and (2) among those reporting lifetime use: (a) lifetime microdosing and (b) use motives. Lifetime and past-year psychedelic use were 27.7% and 11.9% (commonly...

DOI: 10.1080/02791072.2026.2685527 (opens in new tab) Addiction Young adult Product mathematics Substance use +1

Psychedelics, the media portrayal and large-language model evaluations

BJPsych Open June 18, 2026 Catherine L. Clelland

Psychedelics were used for centuries in healing and spiritual rituals, long before the mid-20th century when they became subjects of biomedical research. Although initial trials generated optimism, these were quickly overshadowed by sensationalist media coverage and political backlash. Following decades of inactivity, research on compounds including 3,4-methylenedioxymethamphetamine (MDMA) has...

DOI: 10.1192/bjo.2026.12025 (opens in new tab) Full text (opens in new tab) Sensationalism Politics Field mathematics Headline +10

Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.

Proceedings of the National Academy of Sciences June 16, 2026 Adam R Pines, Xue Zhang, John Kochalka et al.

Psychedelic drugs are poised to become mainstream treatments, yet we lack a circuit-level account of how they reshape brain activity. Emerging evidence suggests that multiple psychedelic compounds modulate activity in the brain's default mode network (DMN), often interpreted as either increased or decreased bottom-up hierarchical processing. Most imaging studies, however, quantify activity as...

DOI: 10.1073/pnas.2522000123 (opens in new tab) Full text (opens in new tab) Default mode network Cortical propagations Hierarchical processing Neuroimaging +1

Music Playlist Use in Clinical Trials of Psychedelic Assisted Psychotherapy: A Systematic Review

Journal of Clinical Psychology June 15, 2026 Lucas Cruz, Fernando R. Beserra, Julia M.k. Freind et al.

Recent studies have shown promising results for psychedelics in the treatment of psychiatric disorders. Both in clinical and recreational settings, contextual elements, such as music, can influence the experience of users and may be linked to positive outcomes. This systematic review identifies how music is being selected and used in psychedelisc-assisted psychotherapy (PAP). The search adopted...

DOI: 10.1002/jclp.70167 (opens in new tab) Psilocybin Music therapy Clinical trial Scopus +8

The effects of psychedelics on attention deficit and hyperactivity disorder - a systematic review.

Acta Neuropsychiatrica June 10, 2026 Helerin Raikkerus, Andrea Bujour, Mark Kennedy et al.

Attention deficit and hyperactivity disorder (ADHD) is a prevalent neuropsychiatric disorder (Drechsler et al., 2020). Recently, psychedelics have become of interest regarding developing treatment options for ADHD. The aim of this systematic review is to find all studies from the APA PsychInfo and MEDLINE databases, where psychedelics have been used for ADHD and assess whether further clinical...

Emergence of synthetic drugs in South America: insights from Brazil, Chile, and Colombia.

Harm Reduction Journal June 4, 2026 Ignacio Bórquez, Bruno Pantaleão, Gabriela Brogim et al.

The illicit drug landscape in South America is going through a major shift. The appearance of Tusi (or "pink cocaine"), a mixture often containing ketamine and MDMA, along with the growing presence of synthetic opioids like fentanyl and nitazenes, signals a new chapter in the region's drug use, which has been traditionally dominated by alcohol, cannabis, and cocaine. Drawing on data on...

DOI: 10.1186/s12954-026-01480-4 (opens in new tab) Full text (opens in new tab) Ketamine Harm reduction Nitazenes Novel psychoactive substances +4

Psychedelic Renaissance: A New Paradigm in Mental Health

European Psychiatry June 1, 2026 A. M. Matas Ochoa, A. R. Quiroga, I. D. Sacristán

Introduction Psychedelics are hallucinogenic agents that are awakening scientific interest in recent years, especially in the field of mental health. Psychedelics induce non-ordinary states of consciousness and alterations in the emotions and in cognition and could be beneficial in treating some mental illness. Objectives The objective of the poster is to expand knowledge about emerging...